Study on urethroplasty for urethral stricture disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to gather prospective evidence on the effectiveness of urethroplasty as a treatment for urethral stricture disease, which is considered the gold standard due to its higher long-term success rates compared to other treatments. It will include diverse patient groups, such as native men, native women, transmen, transwomen, and children, to ensure comprehensive data collection. The study will focus on understanding outcomes across these subgroups to address biases present in previous retrospective studies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Voluntarily signed written informed consent according to the rules of Good Clinical Practice (Declaration of Helsinki) and national regulations.
* Patient age ≥ 6 years.
* If a patient reaches the age of 18 years, he or she will have to provide a new voluntarily signed written informed consent. All patients reaching the age of 18 years will be contacted by the Principal Investigator or Subinvestigator to provide a new voluntarily signed written informed consent.

Exclusion Criteria:

\- Absence of signed written informed consent and thus a patient unwilling to participate.

Where it's running

• University Hospital Ghent
  Ghent, Belgium Recruiting
• Dept. of Urology, Ghent University Hospital
  Ghent, Belgium Not yet recruiting

Study contacts

• Principal investigator: Nicolaas Lumen — University Hospital, Ghent
• Study coordinator: Nicolaas Lumen
• Email: nicolaas.lumen@uzgent.be
• Phone: +32 9 332 22 76

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Comparing cheek (buccal) tissue versus penile skin grafts for repairing long anterior urethral strictures

  This will test whether cheek (buccal) tissue or penile skin works better to repair long anterior urethral strictures in men who need urethroplasty.

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• Paclitaxel-coated versus standard dilatation balloon for recurrent urethral stricture

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• Database for patients with urethral stricture undergoing surgery

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  Recruiting Medical University of Graz · Graz, Styria · NCT06362083

• Using engineered urethral constructs to treat urethral strictures in men

  This study is testing a new way to treat urethral strictures in men by using specially grown tissue from their own bladder to see if it helps them feel better over time.

  Recruiting Phase 1 Wake Forest University Health Sciences · San Francisco, California and 1 other locations · NCT03258658

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.