Database for patients with urethral stricture undergoing surgery
Official title: Construction of a Clinical Urethral Stricture Database for a Prospective Longitudinal Cohort Study
Run by Medical University of Graz · NCT06362083 · Data updated 2026-11-12
This study is trying to gather information from patients with urethral stricture who are having surgery to see how well different surgical methods work and how they affect quality of life.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | Men only |
| Enrollment | 500 (estimated) |
| Sponsor | Medical University of Graz Academic / other |
| Locations | 1 site (Graz, Styria) |
| Status | Recruiting |
| Started | January 15, 2024 |
| Main results expected | January 15, 2034 |
| Study ends | March 15, 2034 |
| Registry record updated | April 12, 2024 |
| Trial ID | NCT06362083 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients scheduled for urethral surgeries such as internal urethrotomy, urethral plastic surgeries, or hypospadias corrections.
✕Probably not a fit
Patients who lack the capacity to consent will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to create a prospective clinical database for patients undergoing various urethral surgeries due to urethral stricture. It will collect pre-operative, intraoperative, and postoperative data, including follow-up information through questionnaires. The main goals are to determine the success rates of these surgeries over different time frames and to identify risk factors for recurrence of urethral stricture. Additionally, the study will assess the quality of life before and after surgery to compare different surgical techniques and improve patient counseling.
Why it matters
Potential benefit: If successful, this study could lead to improved surgical outcomes and better-informed treatment options for patients with urethral stricture.
How similar studies have gone: While there is limited scientific data on urethral surgeries, this approach aims to fill a gap in the existing literature and is considered novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: All patients undergoing any of the following urethral surgeries are included: * Internal urethrotomy according to Sachse (endoscopic transurethral urethrotomy) * End-to-end anastomosis * Urethral plastic surgeries with oral mucosa graft (potentially penile skin) * Urethral plastic surgeries with mesh graft * Hypospadias corrections * Boutonniere * (Self) bougienage of the urethra Exclusion Criteria: * Lack of capacity to consent
Where it's running
-
Röthl Martina Anna
Graz, Styria, Austria Recruiting
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Intraoperative Lidocaine or Dexmedetomidine to Help Postoperative Pain After Urethral Reconstruction
This study tests whether giving lidocaine or dexmedetomidine during urethral reconstruction can reduce pain after surgery and lower the chance of long-lasting pain.
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Urethral Resistive Index (URI) as a non-invasive test for urethral blockage
This project tests a new, painless urine-flow measure called the Urethral Resistive Index (URI) to see if it can detect urethral strictures in men.
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Comparing cheek (buccal) tissue versus penile skin grafts for repairing long anterior urethral strictures
This will test whether cheek (buccal) tissue or penile skin works better to repair long anterior urethral strictures in men who need urethroplasty.
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Paclitaxel-coated versus standard dilatation balloon for recurrent urethral stricture
This trial tests if a paclitaxel-coated dilatation balloon (Optilume) reduces the chance of urethral stricture coming back compared with a non-coated balloon in adults who have had previous dilations or DVIU.
-
Study on urethroplasty for urethral stricture disease
This study is testing how well urethroplasty works for treating urethral stricture disease in different groups of people, including men, women, transgender individuals, and children.
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Using engineered urethral constructs to treat urethral strictures in men
This study is testing a new way to treat urethral strictures in men by using specially grown tissue from their own bladder to see if it helps them feel better over time.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.