Intraoperative Lidocaine or Dexmedetomidine to Help Postoperative Pain After Urethral Reconstruction

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized approach compares perioperative intravenous lidocaine, dexmedetomidine, and placebo during urethral reconstructive surgery. It aims to measure postoperative pain intensity, recovery quality, and the development of chronic postoperative pain, including neuropathic features. The protocol uses established dosing within standard practice to assess potential benefits in pain modulation and opioid-sparing effects. Eligible participants are adults aged 18-75 with ASA I-III status undergoing urethral reconstruction. Outcomes will inform whether perioperative pharmacologic strategies can reduce the transition from acute to chronic pain in this surgical population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* ASA status less or equal 3
* Scheduled for reconstructive surgery of urethra
* Able to understand information provided and to sign informed consent for participation in the study

Exclusion Criteria:

* known allergy to one of the investigated medications
* current chronic pain
* known chronic use of opioids, gabapentinoids and antidepressants

Where it's running

• Department of Anesthesiology and Intensive Care, Centre of Postgraduate Medical Education
  Warsaw, Poland Recruiting

Study contacts

• Study coordinator: Bartosz Horosz, MD,PhD
• Email: bartosz.horosz@gmail.com
• Phone: 0048225841122

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Using engineered urethral constructs to treat urethral strictures in men

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.