Comparing cheek (buccal) tissue versus penile skin grafts for repairing long anterior urethral strictures

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional surgical comparison enrolls men with long segment anterior urethral strictures and compares dorsal onlay buccal mucosal graft (BMG) urethroplasty to penile skin graft (PSG) urethroplasty. Eligible patients typically have strictures longer than 1 cm with spongiofibrosis and prior failed dilation or DVIU, while those with lichen sclerosus, prior hypospadias repair, or previous failed urethroplasty are excluded. Surgeons perform substitution urethroplasty using the assigned graft type and patients are followed for functional outcomes, complications, and stricture recurrence. The goal is to determine which graft yields better urinary function and fewer complications in this setting.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with long segment anterior urethral stricture that was defined as a stricture with a length of more than 1 cm with spongiofibrosis.
* Patients with previous failed urethral dilatation or direct vision internal urethrotomy (DVIU)

Exclusion Criteria:

* Patients with lichen sclerosus
* Patients with history of hypospadias repair
* Patients with recurrent urethral stricture after failed previous urethroplasty

Where it's running

• Tanta University
  Tanta, El-Gharbia Governorate, Egypt, Egypt Recruiting

Study contacts

• Study coordinator: Mohamed I Elmaadawy, MD
• Email: Mohamed.elmaadawy@med.tanta.edu.eg
• Phone: 00201060245430

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• General versus spinal anesthesia with local numbing for buccal mucosal graft urethroplasty

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• Urethral Resistive Index (URI) as a non-invasive test for urethral blockage

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• Fat graft beneath penile skin graft during reconstruction

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• Oral mucosa versus labial grafts for female urethral reconstruction

  This trial will see if oral mucosal grafts or labial grafts work better for women having urethroplasty to treat urethral stricture.

  Recruiting Tanta University · Tanta, El-Gharbia · NCT07153861

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.