Standardizing tests that detect spatial neglect.
Official title: Standardization of Spatial Neglect Assessment Tests in a Francophone Population
Run by Assistance Publique - Hôpitaux de Paris · NCT07145970 · Data updated 2026-11-12
This project will test neuropsychological tasks in healthy French-speaking adults to create reference scores that help clinicians decide when a person has spatial neglect.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 20 Years to 89 Years |
| Sex | All |
| Enrollment | 210 (estimated) |
| Sponsor | Assistance Publique - Hôpitaux de Paris Academic / other |
| Locations | 1 site (Garche) |
| Status | Recruiting |
| Started | January 7, 2026 |
| Main results expected | January 7, 2027 |
| Study ends | January 7, 2027 |
| Registry record updated | February 10, 2026 |
| Trial ID | NCT07145970 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Healthy French-speaking adults aged 20–89 with no history of central neurological disease, sufficient corrected near vision, and capacity to consent are the intended participants.
✕Probably not a fit
People with prior stroke, transient ischemic attack, multiple sclerosis, epilepsy, significant uncorrected visual impairment, or abnormal neurological exams are excluded and would not benefit from participating in the norming effort.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The study will enroll 210 healthy volunteers aged 20–89 at the neurovascular department of Raymond-Poincaré Hospital to generate normative data for visual, tactile, personal and motor neglect tests. Investigators will administer French-language versions of target cancellation tasks (including an Apples-style test), tactile midpoint and exploration tasks, and a simplified Comb and Razor Test under standardized conditions. Exclusion criteria remove individuals with prior central neurological disease or significant uncorrected visual impairment to ensure norms reflect non-pathological variation by age, sex, handedness and education. The resulting reference values will be used to define pathological thresholds for diagnosing different types of spatial neglect in clinical populations.
Why it matters
Potential benefit: If successful, clinicians will have validated French reference norms for multiple spatial neglect tests, improving diagnostic accuracy and interpretation of patient results.
How similar studies have gone: Related target-cancellation and tactile neglect tests have produced useful normative and diagnostic data in English-speaking cohorts, but a validated French-language standardization is novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Healthy volunteer attending the neurovascular department of Raymond-Poincaré Hospital 2. Aged between 20 and 89 years 3. Affiliated with a health insurance scheme 4. French-speaking 5. Has freely and knowingly expressed their non-opposition Exclusion Criteria: 1. Known history of central neurological disease: stroke (ischemic or hemorrhagic), transient ischemic attack, encephalitis, multiple sclerosis, or epilepsy. 2. Medical interview suggesting past central nervous system involvement: history of episodes such as sensorimotor deficits, dysarthria, aphasia, blurred or double vision, or positive symptoms such as visual or sensory hallucinations (e.g., paresthesias). 3. Significant visual impairment - as judged by the examiner - in near vision despite correction, or monocular blindness. Specifically, inability to distinguish the targets with gaps in the example (pre-test) of the Apples Cancellation Test. 4. Abnormal neurological examination: 1. National Institutes of Health Stroke Scale (NIHSS) score \> 0 2. Pyramidal reflex syndrome (hyperactive deep tendon reflexes with extended reflexogenic zones and spread). 5. Use of substances (alcohol or drugs) within 24 hours prior to the assessment. 6. Presence of cognitive or psychiatric disorders, assessed during the inclusion interview and neurological examination, at the examiner's discretion. 7. Language barrier or aphasia, assessed during the inclusion interview and neurological examination, at the examiner's discretion. 8. Participant under legal protection (guardianship, curatorship, or legal safeguard).
Where it's running
-
CHU Raymond Poincarré
Garche, France Recruiting
Study contacts
- Study coordinator: Jean-Baptiste BRUNET de COURSSOU, Dr
- Email: jean-baptiste.brunet-de-courssou@aphp.fr
- Phone: +33 1 47 10 72 55
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.