Motor and cognitive function testing for people with brain injury and cerebral palsy
Official title: Studies of the Diagnosis, Rehabilitation and Links Between Motor and Cognitive Functions in Acquired and Developmental Brain Damaged Patients
Run by Cliniques universitaires Saint-Luc- Université Catholique de Louvain · NCT02543424 · Data updated 2026-11-12
This project will test combined motor and thinking assessments and new therapy ideas for children and adults with brain damage such as cerebral palsy or stroke who have upper‑limb weakness or neglect.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 5 Years and up |
| Sex | All |
| Enrollment | 400 (estimated) |
| Sponsor | Cliniques universitaires Saint-Luc- Université Catholique de Louvain Academic / other |
| Locations | 2 sites (Ottignies, Brabant Wallon and 1 other locations) |
| Status | Recruiting |
| Started | April 2015 |
| Main results expected | December 2028 |
| Study ends | December 2028 |
| Registry record updated | April 27, 2026 |
| Trial ID | NCT02543424 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are children and adults (ages 3–90) with congenital cerebral palsy or acquired brain injury who have upper limb weakness or hemineglect and can understand simple verbal instructions.
✕Probably not a fit
Patients with IQ below 70, severe aphasia, major attentional or psychiatric disorders, or progressive neurodegenerative diseases are excluded and unlikely to benefit from this protocol.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional project brings together motor, cognitive, and neuropsychological testing in children and adults with acquired or developmental brain damage as well as healthy participants. Participants aged 3–90 who present upper limb paresis or hemineglect and can follow simple verbal instructions will complete standardized motor and cognitive assessments. Investigators will compare patient and healthy profiles to map links between movement and cognitive abilities. Findings will be used to propose novel rehabilitation approaches that combine motor and cognitive training.
Why it matters
Potential benefit: If successful, combined motor‑cognitive therapies could improve both movement and thinking, leading to better everyday function for people with brain damage.
How similar studies have gone: Previous studies have shown links between motor and cognitive abilities, but combined motor‑cognitive therapy approaches remain relatively novel and not yet widely proven.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Congenital cerebral palsy and acquired brain injury children and adult patients * Presenting upper limb paresis and/or hemineglect * Between the age of 3 to 90. * Able to understand and carry out simple verbal instruction Exclusion Criteria: * IQ \< 70 * Severe aphasia, attentional disorder or psychiatric disorders * Neurodegenerative disorders
Where it's running
-
Centre Hospitalier Neurologique William Lennox
Ottignies, Brabant Wallon, Belgium Recruiting -
Cliniques Universitaires St Luc
Woluwé-Saint-Lambert, Brussels Capital, Belgium Recruiting
Study contacts
- Principal investigator: Thierry Lejeune — St. Luc Hospital
- Study coordinator: Marie Alsamour
- Email: marie.alsamour@uclouvain.be
Similar studies
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.