Motor and cognitive function testing for people with brain injury and cerebral palsy
Studies of the Diagnosis, Rehabilitation and Links Between Motor and Cognitive Functions in Acquired and Developmental Brain Damaged Patients
This project will test combined motor and thinking assessments and new therapy ideas for children and adults with brain damage such as cerebral palsy or stroke who have upper‑limb weakness or neglect.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 400 (estimated) |
| Ages | 5 Years and up |
| Sex | All |
| Sponsor | Cliniques universitaires Saint-Luc- Université Catholique de Louvain Academic / other |
| Locations | 2 sites (Ottignies, Brabant Wallon and 1 other locations) |
| Trial ID | NCT02543424 on ClinicalTrials.gov |
What this trial studies
This interventional project brings together motor, cognitive, and neuropsychological testing in children and adults with acquired or developmental brain damage as well as healthy participants. Participants aged 3–90 who present upper limb paresis or hemineglect and can follow simple verbal instructions will complete standardized motor and cognitive assessments. Investigators will compare patient and healthy profiles to map links between movement and cognitive abilities. Findings will be used to propose novel rehabilitation approaches that combine motor and cognitive training.
Who should consider this trial
Good fit: Ideal candidates are children and adults (ages 3–90) with congenital cerebral palsy or acquired brain injury who have upper limb weakness or hemineglect and can understand simple verbal instructions.
Not a fit: Patients with IQ below 70, severe aphasia, major attentional or psychiatric disorders, or progressive neurodegenerative diseases are excluded and unlikely to benefit from this protocol.
Why it matters
Potential benefit: If successful, combined motor‑cognitive therapies could improve both movement and thinking, leading to better everyday function for people with brain damage.
How similar studies have performed: Previous studies have shown links between motor and cognitive abilities, but combined motor‑cognitive therapy approaches remain relatively novel and not yet widely proven.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Congenital cerebral palsy and acquired brain injury children and adult patients * Presenting upper limb paresis and/or hemineglect * Between the age of 3 to 90. * Able to understand and carry out simple verbal instruction Exclusion Criteria: * IQ \< 70 * Severe aphasia, attentional disorder or psychiatric disorders * Neurodegenerative disorders
Where this trial is running
Ottignies, Brabant Wallon and 1 other locations
- Centre Hospitalier Neurologique William Lennox — Ottignies, Brabant Wallon, Belgium (Recruiting)
- Cliniques Universitaires St Luc — Woluwé-Saint-Lambert, Brussels Capital, Belgium (Recruiting)
Study contacts
- Principal investigator: Thierry Lejeune — St. Luc Hospital
- Study coordinator: Marie Alsamour
- Email: marie.alsamour@uclouvain.be
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.