Assessing normal cardiac values using MRI in healthy adults
Official title: A Multicenter Investigation of Cardiac Normal Values of Morphology, Function and Tissue Characteristics by Magnetic Resonance Imaging
Run by Chinese Academy of Medical Sciences, Fuwai Hospital · NCT05346094 · Data updated 2026-11-12
This study is trying to find out what healthy hearts look like in Chinese adults by using MRI to create a guide for doctors to better understand heart health.
Quick facts
| Study type | Observational |
|---|---|
| Ages | Any age to 80 Years |
| Sex | All |
| Enrollment | 938 (estimated) |
| Sponsor | Chinese Academy of Medical Sciences, Fuwai Hospital Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Status | Recruiting |
| Started | January 1, 2022 |
| Main results expected | December 31, 2026 |
| Study ends | June 30, 2027 |
| Registry record updated | January 4, 2023 |
| Trial ID | NCT05346094 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are healthy adults without any cardiovascular disease or related risk factors.
✕Probably not a fit
Patients with existing cardiovascular diseases or serious non-cardiovascular conditions will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study enrolls healthy volunteers to establish age and sex-specific reference values for normal cardiac structure and function in Chinese adults. Utilizing cardiovascular magnetic resonance (CMR) techniques, including steady-state free precession (SSFP) and novel methods for myocardial strain and tissue characterization, the study aims to create a comprehensive database of normal cardiac parameters. This database will serve as a crucial reference for diagnosing and evaluating cardiovascular diseases, particularly in the Chinese population, where such standards are currently lacking.
Why it matters
Potential benefit: If successful, this study could provide essential reference values that improve the diagnosis and management of cardiovascular diseases in the Chinese population.
How similar studies have gone: While there are existing reference standards for normal cardiac values globally, this study is novel in its focus on a large sample of the Chinese population and the inclusion of advanced CMR parameters.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Subjects without cardiovascular disease, cardiovascular related symptoms and risk factors judged by combining clinical manifestations, non-invasive imaging and laboratory examination Exclusion Criteria: * Subjects clinically screened or previously diagnosed with cardiovascular disease and risk factors * Subjects with serious non-cardiovascular diseases * Subjects with poor quality of magnetic resonance imaging * Subjects refused to participate in the study * Subjects with contraindications to MRI
Where it's running
-
Fuwai Hospital
Beijing, Beijing Municipality, China Recruiting
Study contacts
- Study coordinator: Minjie Lu
- Email: coolkan@163.com
- Phone: 13681042022
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.