Spinal cord stimulation to help arm and leg movement after stroke

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional trial will evaluate the safety and potential benefit of implanting a spinal cord stimulator in patients with persistent post-stroke limb motor impairment. Eligible participants are adults aged 20–80 with one prior stroke and limited motor function who have completed rehabilitation. The study will monitor motor outcomes, safety signals, and overall quality of life to determine if the device can augment recovery when added to ongoing therapy.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Hemiparesis resulting from a single ischemic or hemorrhagic stroke, with a disease duration of ≥6 months.
2. Aged between 20 and 80 years (inclusive).
3. Received regular rehabilitation therapy after stroke but with poor recovery of limb motor function; Fugl-Meyer Assessment upper extremity score \>7 and \<45, and lower extremity score \>5 and \<30.
4. Partially preserved sensory function.

Exclusion Criteria:

1. Severe systemic diseases (e.g., neurological disorders other than stroke, cancer, severe circulatory or respiratory diseases, liver or kidney failure, etc.) or other conditions that may impair the subject's motor or cognitive function.
2. Presence of spinal cord-related nerve compression that could cause severe functional impairment.
3. Women who are pregnant or breastfeeding.
4. Use of anticoagulant, antiplatelet, antispasmodic, or antiepileptic medications prior to enrollment or during the study period.
5. Severe joint contracture that, in the clinical investigator's opinion, precludes participation in the study.
6. Severe mental illness or intellectual disability that prevents cooperation with treatment or follow-up questionnaires, with a Mini-Mental State Examination (MMSE) score \<24.
7. Presence of other implanted medical devices.
8. Severe claustrophobia.

Where it's running

• The Second Affiliated Hospital, Zhejiang University School of Medicine
  Hangzhou, Zhejiang, China Recruiting

Study contacts

• Study coordinator: Gao Chen
• Email: d.chengao@163.com
• Phone: 0571-87784713

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Dual-task balance training plus computer-based cognitive training after stroke

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  Recruiting Matia Foundation · San Sebastián, GUIPUZCOA · NCT07913620

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.