SOFA-2 scoring for ICU patients in Türkiye
Real-Time Validation and Feasibility of the SOFA-2 Score in Adult Intensive Care Units in Türkiye (TR-SOFA2): A Multicenter Prospective Observational Study
This project will test whether the updated SOFA-2 organ failure score predicts survival for adults admitted to intensive care units in Türkiye.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 5200 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Izmir Dr Suat Seren Chest Diseases and Surgery Education and Research Hospital Academic / other |
| Locations | 1 site (Izmir, İzmir) |
| Trial ID | NCT07338240 on ClinicalTrials.gov |
What this trial studies
This multicenter prospective observational project will follow adult patients admitted to participating ICUs in Türkiye and record routinely collected clinical and laboratory data. SOFA and SOFA-2 scores will be calculated from data obtained during the first 24 hours of ICU admission and again at 72 hours for longer stays. No extra tests or treatments will be performed beyond standard clinical care. Patients will be followed until ICU discharge or death to measure the relationship between SOFA-2 scores and ICU mortality. The study will also compare SOFA-2 performance against the original SOFA score and account for differences across centers.
Who should consider this trial
Good fit: Adults aged 18 or older admitted to a participating intensive care unit in Türkiye who remain in the ICU for more than 24 hours (excluding pregnant patients and organ donors) are the intended candidates.
Not a fit: Patients under 18, pregnant patients, organ donors, those discharged or transferred within 24 hours, or those with unknown ICU outcomes are unlikely to benefit from this study's findings.
Why it matters
Potential benefit: If successful, SOFA-2 could give clinicians a more accurate way to predict ICU mortality and help guide triage and monitoring decisions.
How similar studies have performed: The original SOFA score is widely validated for ICU mortality prediction, while SOFA-2 is a newer update with limited external validation to date.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 18 years or older * Admission to a participating intensive care unit in Türkiye * Intensive care unit stay longer than 24 hours Exclusion Criteria: * Patients younger than 18 years * Pregnant patients * Organ donors * Patients with unknown intensive care unit discharge outcomes
Where this trial is running
Izmir, İzmir
- University of Health Sciences Turkey, İzmir School of Medicine, Dr. Suat Seren Chest Disease and Thoracic Surgery Training and Research Hospital, Intensive Care Unit — Izmir, İzmir, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: Süleyman Yıldırım, Assoc. Prof.
- Email: deu.syldrm@gmail.com
- Phone: +905057143243
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.