Sleep-friendly Seizure Risk with Wearable EEGs

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will use the Dreem headband to monitor sleep and brain activity over extended periods while participants keep stable medications. They will analyze how sleep timing, duration, and structure relate to interictal discharges and seizure events. A new Sleep-Sensitive Epilepsy Risk Index (SERI) will be developed to predict seizure risk tied to sleep disruption. The study aims to identify which patients are most affected by sleep changes and to inform more personalized care. Data will be collected in the Duke University Health System to reflect real-world conditions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age \> 18 years
* At least 2 seizures per week based on clinical notes
* Patients where medications will stay stable over the study period
* 40% of both spikes and spindles are identifiable on the dreem headband based on the screening night

Exclusion Criteria:

* Cognitive impairment
* Psychiatric comorbidities which may influence sleep
* No bedpartner/caregiver to observe seizures
* Low agreement (below 60%) between Dreem's sleep scoring and manual scoring will be excluded from the study
* Apnea-hypopnea index of \> 10/h

Where it's running

• Duke University Health System
  Durham, North Carolina, United States Recruiting

Study contacts

• Principal investigator: Birgit Frauscher, MD PD — Duke University
• Study coordinator: Birgit Frauscher, MD PD
• Email: birgit.frauscher@duke.edu
• Phone: 9196139386

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.