Sleep apnea biomarkers and CPAP use after diagnosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, multicenter observational cohort study of adults with newly diagnosed obstructive sleep apnea who are prescribed CPAP. Baseline data include demographic details, medical history, symptom questionnaires, and biomarkers derived from initial sleep studies, such as hypoxic burden, pulse wave amplitude drop index, and heart rate response. CPAP adherence is measured at roughly 12 weeks, with additional follow-up for clinical characteristics, quality of life, and potential biomarker changes if a follow-up sleep study is performed as part of routine care. The primary aim is to examine associations between baseline biomarkers and CPAP adherence, while secondary analyses explore biomarker distributions across clinical factors and their relationship with symptoms and outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Newly diagnosed obstructive sleep apnea with an indication for continuous positive airway pressure therapy
* Age older than 18 years
* Written informed consent obtained

Exclusion Criteria:

* Continuous positive airway pressure treatment during the preceding 3 months
* Medical contraindication to continuous positive airway pressure therapy
* Concomitant condition likely to affect adherence to continuous positive airway pressure, including severe cognitive impairment or an unstable psychiatric disorder

Where it's running

• Clinique Millenaire
  Montpellier, France Recruiting

Study contacts

• Study coordinator: Francois FB Bughin, MD, PhD
• Email: fbughin@hotmail.com
• Phone: 0033761783081

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.