Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Short-Term Intensive PTSD Treatment for Military Personnel

Official title: Examining the Efficacy of Short-Term Intensive PTSD Treatment on Psychological and Cognitive Impairment Symptoms

Run by Ohio State University · NCT07680517 · Data updated 2026-11-12

This trial tests whether a brief, massed form of CPT and EMDR can quickly reduce PTSD symptoms and related cognitive problems in active-duty military personnel.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment120 (estimated)
SponsorOhio State University
Academic / other
Locations1 site (Fayetteville, North Carolina)
StatusRecruiting
StartedApril 1, 2026
Main results expectedAugust 2028
Study endsAugust 2028
Registry record updatedJuly 2, 2026
Trial IDNCT07680517 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are active-duty military personnel (JSOC-aligned) aged 18 or older with PTSD or subthreshold PTSD (3 of 4 symptoms) who can consent in English and participate in massed therapy.

Probably not a fit

Individuals with active substance use disorder requiring medical management, imminent suicide risk needing inpatient care, or inability to provide informed consent may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Participants are treatment-seeking military personnel with PTSD or subthreshold PTSD. The study uses a massed format, delivering CPT and EMDR in a condensed 2–3 week period to see if rapid, sustained symptom and cognitive improvements can be achieved in real-world military settings. Treatments are standard, evidence-based psychotherapies (CPT and EMDR) and delivered in an operational military environment. Outcomes focus on PTSD symptom changes and cognitive performance. The study is led by Ohio State University with support from the Congressionally Directed Medical Research Programs and is conducted at Fort Bragg.

Why it matters

Potential benefit: If successful, participants may experience faster relief from PTSD symptoms and improved cognitive functioning.

How similar studies have gone: Prior randomized trials support CPT and EMDR for PTSD, and massed delivery has shown promise in reducing symptoms more quickly in some populations.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

-Treatment-seeking military personnel (i.e., any assigned or aligned JSOC personnel) who meet diagnostic criteria for PTSD or subthreshold PTSD (i.e., meeting diagnostic threshold for 3 of 4 symptom criteria who are (1) 18 years of age or older; (2) current diagnosis of PTSD or subthreshold PTSD (i.e. meeting diagnostic criteria for 3 of 4 symptom criteria, assessed using the DIAMOND); (3) current military personnel; (4) ability to speak and understand the English language; and (5) ability to complete the informed consent process

Exclusion Criteria:

* (1) substance use disorder requiring medical management; (2) imminent suicide risk warranting inpatient hospitalization or suicide-focused treatment; and (3) impaired mental status that precludes the ability to provide informed consent (e.g., intoxication, psychosis, mania).

Where it's running

  • Fort Bragg
    Fayetteville, North Carolina, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.