Clinical trial Recruiting at 1 site Interventional Ages 18 to 70

Exposure by Assessment: Testing AMQ-based EMA on Intrusive Trauma Memories in PTSD

Official title: Exposure by Assessment: Effects of Daily AMQ-Based EMA of an Intrusive Trauma Memory in PTSD

Run by Tel Aviv University · NCT07658157 · Data updated 2026-11-12

We’re testing whether daily prompts to focus on a traumatic memory (vs. a neutral memory) using a simple at-home EMA can reduce intrusive PTSD memories and overall PTSD symptoms.

Quick facts

Study typeInterventional
Ages18 Years to 70 Years
SexAll
Enrollment50 (estimated)
SponsorTel Aviv University
Academic / other
Locations1 site (Tel Aviv)
StatusRecruiting
StartedJune 14, 2026
Main results expectedOctober 2026
Study endsJune 2027
Registry record updatedJune 25, 2026
Trial IDNCT07658157 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18-70 with PTSD and prominent intrusive symptoms.

Probably not a fit

Individuals without intrusive symptoms or with conditions excluding study criteria may not benefit from this approach.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study compares two at-home EMA approaches for adults with PTSD: prompts about an intrusive trauma memory or prompts about an emotionally neutral memory. It aims to see if actively focusing on the trauma memory in daily prompts can lessen intrusion severity and overall PTSD symptoms. The design involves minimal clinician input and uses a home-based, remote protocol to capture how memory-focused prompts influence real-world symptom experiences. Prior work suggested potential intrusion reductions with memory-focused EMA, but lacked a control, so this trial includes a neutral-memory control to clarify target effects. The goal is to determine whether this brief, remote intervention is feasible and potentially beneficial for reducing intrusive symptoms.

Why it matters

Potential benefit: If successful, participants may experience fewer intrusive memories and overall PTSD symptoms through a simple, low-burden at-home intervention.

How similar studies have gone: Previous exploratory work hinted at intrusion reductions with memory-focused EMA, but results were inconclusive without a proper control group.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults aged 18-70
* Posttraumatic stress disorder
* intrusive symptoms.

Exclusion Criteria:

* Psychotic or bipolar disorder
* Heavy use of drugs or alcohol
* Prominent personality disorder
* Significant risk of harm to self or others
* Current trauma-focused treatment
* Reporting intrusions as thoughts only rather than as memories

Where it's running

  • Tel Aviv University
    Tel Aviv, Israel
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.