Shanghai registry of ischemic stroke with focus on younger adults
Official title: Shanghai Prospective Registry Study of Ischemic Stroke
Run by Huashan Hospital · NCT07171242 · Data updated 2026-11-12
This project will collect medical and imaging information from adults in Shanghai who had an imaging-confirmed ischemic stroke to see what causes, risk factors, treatments, and outcomes look like, with extra focus on people under 55.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 15000 (estimated) |
| Sponsor | Huashan Hospital Academic / other |
| Locations | 1 site (Shanghai, Shanghai Municipality) |
| Status | Recruiting |
| Started | December 1, 2024 |
| Main results expected | December 31, 2029 |
| Study ends | December 31, 2029 |
| Registry record updated | September 12, 2025 |
| Trial ID | NCT07171242 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18 or older with a clinical and imaging-confirmed acute or subacute ischemic stroke who can provide informed consent are the intended participants, with particular attention to those under 55.
✕Probably not a fit
People without imaging confirmation, those with excessive missing data (>40%), those who cannot be followed or consent, or those not treated/seen within the participating center are unlikely to benefit from this registry.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective cohort registry using the 4S database to enroll adults with imaging-confirmed ischemic stroke treated at Huashan Hospital, Fudan University. The protocol emphasizes young-onset stroke (typically <55 years) and will collect clinical, imaging, treatment, and outcome data over time. Analyses will examine traditional and emerging risk factors (for example hypertension, diabetes, air pollution, and lifestyle changes), the relationship between reperfusion and secondary prevention strategies and outcomes, and issues in genetic young-stroke patients including Fabry-related syndromes. The registry aims to characterize incidence, etiologic trends, and pathophysiological mechanisms of young-onset stroke in the Shanghai region.
Why it matters
Potential benefit: If successful, the registry could identify common causes and modifiable risk factors in younger stroke patients and guide better prevention and treatment strategies locally.
How similar studies have gone: Other regional and national stroke registries have successfully clarified risk patterns and treatment outcomes in young stroke populations, though the combination of Shanghai-specific environmental trends and genetic screening adds a more novel regional focus.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Patients aged 18 years or older diagnosed with acute or subacute ischemic stroke 2. The diagnosis of stroke must be confirmed through clinical assessment and imaging examinations 3. In cases where imaging examinations are negative or unavailable, the clinical diagnosis of stroke must be confirmed by an experienced neurologist. (4)Patients must sign an informed consent form agreeing to the collection of information. Exclusion Criteria: 1. The amount of missing data exceeds 40% of the data to be entered; 2. After enrollment, it is discovered that the study participant does not meet the inclusion criteria or meets any of the exclusion criteria; 3. Missing persons
Where it's running
-
Huashan hospital Fudan University
Shanghai, Shanghai Municipality, China Recruiting
Study contacts
- Study coordinator: Qiang Dong, Professor
- Email: qiang_dong163@163.com
- Phone: +8613701747065
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.