Seeing if ultrasound helps set the right dry weight for people on dialysis
Official title: Contribution of Lung Ultrasound and VExUS Score in Assessment of Volume Status in Maintenance Hemodialysis Patients.
Run by Alexandria University · NCT07721636 · Data updated 2026-11-12
This study tests whether using ultrasound, including VExUS and lung ultrasound, helps doctors better set the dry weight for patients on maintenance hemodialysis.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 25 Years to 65 Years |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Alexandria University Academic / other |
| Locations | 1 site (Alexandria) |
| Status | Recruiting |
| Started | July 1, 2026 |
| Main results expected | December 31, 2026 |
| Study ends | February 28, 2027 |
| Registry record updated | July 23, 2026 |
| Trial ID | NCT07721636 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with ESRD on maintenance hemodialysis for at least three months, able to consent, treated at Alexandria University hospitals.
✕Probably not a fit
Patients with significant right heart disease, cirrhosis, major lung disease, or BMI ≥30 may be less likely to benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
In this prospective, single-arm study, adults on maintenance hemodialysis will be followed for 24 weeks and serve as their own controls. Phase I uses standard clinical assessment to guide dry weight and ultrafiltration targets, while Phase II adds POCUS-based measurements to guide decisions. The researcherswill compare volume status estimates and outcomes between the two phases using both conventional assessments and ultrasound findings. The study collects clinical data, lab tests, dialysis adequacy, and imaging results to understand the potential benefit of POCUS in volume management.
Why it matters
Potential benefit: If successful, POCUS could improve accuracy in determining dry weight and potentially reduce intradialytic symptoms and hospital visits.
How similar studies have gone: Prior work using ultrasound for volume assessment in dialysis shows promise but is still developing in this specific setting.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * ESRD patients on maintenance HD for more than three months. * In the HD unit at the Medical Research Institute and Faculty of Medicine. Alexandria University. * Age: 25 -65 years old. * The ability to give informed consent. Exclusion Criteria: * Patients with previous echocardiographic evidence of right heart dysfunction, tricuspid valve disease, or IVC thrombosis. * Patients with liver cirrhosis * Lung diseases: interstitial lung diseases, COPD patients. * Obese (BMI≥30)
Where it's running
-
Alexandria University Hospitals
Alexandria, Egypt Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.