See if a leg raise before anesthesia helps predict low blood pressure after induction in GI tumor surgery
Official title: Dynamic Changes in Carotid Artery Doppler Parameters Following Passive Leg Raising for Prediction of Post-Induction Hypotension in Patients Undergoing Elective Gastrointestinal Tumor Surgery
Run by Ankara City Hospital Bilkent · NCT07777159 · Data updated 2026-11-12
This study tests whether a passive leg raise, measured with carotid Doppler, can predict post-induction hypotension in adults undergoing elective gastrointestinal tumor surgery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 99 (estimated) |
| Sponsor | Ankara City Hospital Bilkent Academic / other |
| Locations | 1 site (Ankara) |
| Status | Recruiting |
| Started | September 1, 2026 |
| Main results expected | December 2026 |
| Study ends | December 2026 |
| Registry record updated | October 28, 2026 |
| Trial ID | NCT07777159 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) scheduled for elective gastrointestinal tumor surgery under general anesthesia, with BMI under 40 kg/m² and able to consent, and able to undergo carotid Doppler measurements.
✕Probably not a fit
Patients with BMI ≥40, inability to obtain Doppler measurements, or conditions severely limiting hemodynamic assessment may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective observational study enrolls adults planned for elective GI tumor surgery under general anesthesia. Before anesthesia induction, a passive leg raise maneuver will be performed and carotid artery Doppler measurements, along with hemodynamic data, will be collected. The goal is to see if these measurements can predict which patients may develop hypotension after induction. The study does not involve an intervention beyond the leg raise assessment and observational data collection. No treatment changes or randomization are described; results will inform risk prediction for PIH in this surgical population.
Why it matters
Potential benefit: If successful, the approach could help clinicians anticipate and mitigate post-induction hypotension in GI tumor surgery patients.
How similar studies have gone: Prior work in peri-induction hemodynamics suggests Doppler-based predictors can be informative, but this specific passive leg raise approach for PIH prediction is less established and exploratory.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 18 years or older * Patients scheduled for elective gastrointestinal tumor surgery * Surgery planned under general anesthesia * Body mass index (BMI) \<40 kg/m² * Written informed consent provided Exclusion Criteria: * Refusal to participate or inability to obtain written informed consent * Body mass index (BMI) ≥40 kg/m² * Pregnancy * Emergency surgery * Difficult intubation * ASA physical status ≥IV * Pediatric patients (\<18 years) * Inability to perform carotid Doppler measurements * Arrhythmia other than continuous sinus rhythm or uncontrolled cardiac arrhythmia * Severe cardiac dysfunction or left ventricular ejection fraction \<40% * Severe valvular heart disease * Clinically significant autonomic nervous system disorders * Inadequate noninvasive blood pressure monitoring or inability to obtain the required hemodynamic measurements * Active sepsis or systemic inflammatory syndrome * Severe peripheral vascular disease or significant carotid artery stenosis (\>50%) * Severe pulmonary disease or advanced respiratory failure * Implanted cardiac device (pacemaker/ICD) * Baseline mean arterial pressure (MAP) \<65 mmHg * Preoperative systolic blood pressure \>190 mmHg or diastolic blood pressure \>110 mmHg
Where it's running
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Ankara Bilkent City Hospital
Ankara, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Seçilnaz Ünlü Tuncer, Anesthesiology Resident
- Email: secilnaz.unlu@gmail.com
- Phone: +90 553 177 36 18
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.