How often older adults with cancer get a big drop in blood pressure right after anesthesia induction

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective observational study at a single oncology hospital that will record hemodynamic data before and during the first 20 minutes after anesthesia induction in patients aged 65 and older with cancer. Standard monitoring plus perfusion index (PI) and pleth variability index (PVI) readings will be taken and averaged from the non-cannulated hand, and induction drugs and doses will be documented. Demographics, comorbidities, cancer type and treatments, preoperative labs, medications, and ASA score will be collected to analyze associations with post-induction hypotension (PIH), defined as a ≥30% drop in mean arterial pressure or MAP below 65 mmHg within 20 minutes before surgical stimulation. The goal is to identify frequency and modifiable risk factors to inform perioperative management for geriatric oncology patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults ≥65 years of age

Patients with a diagnosis of cancer and scheduled for surgery

Ability and willingness to provide written informed consent

ASA physical status class II-IV

Exclusion Criteria:

Patients under 65 years of age

Patients without a confirmed oncologic diagnosis

Refusal to provide written informed consent

Patients undergoing regional anesthesia

Patients with tracheostomy or requiring multiple intubation attempts

History of peripheral arterial disease

Use of vasopressors before the start of surgery

Uncontrolled hypertension (blood pressure \>180/110 mmHg)

Advanced heart failure (Ejection Fraction \<40%)

Severe arrhythmias such as atrial fibrillation or significant ventricular arrhythmias that preclude reliable hemodynamic monitoring

Where it's running

• Dr. Abdurrahman Yurtaslan Oncology Training and Research Hospital
  Ankara, Ankara, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Dolunay arık
• Email: arikdolunay@gmail.com
• Phone: +90 0554 977 44 97

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.