Second-generation travoprost intracameral implant for open-angle glaucoma and ocular hypertension

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized Phase 2/3 trial compares a second-generation travoprost intracameral implant to timolol 0.5% eye drops given twice daily in adults with open-angle glaucoma or ocular hypertension. Participants are randomized to receive the implant (with sham and placebo controls as appropriate) or topical timolol and are followed for safety and intraocular pressure (IOP) lowering outcomes. Key eligibility includes a diagnosis of open-angle glaucoma or ocular hypertension and excludes eyes with prior incisional glaucoma surgery, prior argon laser trabeculoplasty (ALT), or prior minimally invasive glaucoma surgery (MIGS). The study collects both efficacy endpoints (IOP reduction) and safety data related to the implant and ocular procedures.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis of open-angle glaucoma or ocular hypertension in the study eye

Exclusion Criteria:

* Prior incisional glaucoma surgery in the study eye
* Prior argon laser trabeculoplasty (ALT) in the study eye
* Prior minimally invasive glaucoma (MIGS) surgery in the study eye

Where it's running

• Glaukos Investigative Site
  Grand Junction, Colorado, United States Recruiting
• Glaukos Investigative Site
  Oklahoma City, Oklahoma, United States Recruiting
• Glaukos Clinical Site
  El Paso, Texas, United States Recruiting

Study contacts

• Study coordinator: Study Director
• Email: ClinicalResearch@glaukos.com
• Phone: 949-739-8749

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.