Screening and brief counseling for substance use in adult survivors of childhood cancer
Official title: Piloting the Feasibility of Incorporating a Standardized Substance Use Measure With Linked-Brief Intervention Into Routine Psychosocial Care of Adult Childhood Cancer Survivors
Run by St. Jude Children's Research Hospital · NCT07516301 · Data updated 2026-11-12
This study tests whether a short, evidence-based substance-use screening plus a brief counseling session can be added into routine survivorship care for adult survivors of childhood cancer at St. Jude.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 15 Years and up |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | St. Jude Children's Research Hospital Academic / other |
| Locations | 1 site (Memphis, Tennessee) |
| Status | Recruiting |
| Started | October 2026 |
| Main results expected | October 2027 |
| Study ends | October 2028 |
| Registry record updated | September 3, 2026 |
| Trial ID | NCT07516301 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adult survivors of childhood cancer (≥15 years old) who can read and speak English and are seen in the ACT Clinic at St. Jude.
✕Probably not a fit
Individuals with significant cognitive impairment or who are unable to participate in brief counseling may not benefit from this approach.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
In this pilot study, adult survivors in the ACT Clinic complete the WHO ASSIST questionnaire during a regular visit to identify potential risks with alcohol, tobacco, cannabis, and other substances. Those at moderate or high risk in the intervention group receive a brief counseling session using motivational interviewing to encourage healthier choices. The study assesses whether this screening and intervention can be integrated smoothly into busy clinic workflows, with follow-up surveys at three months to see if substance use changes. Thirty participants will be enrolled to evaluate feasibility, acceptability, and fidelity, with results guiding a larger future study.
Why it matters
Potential benefit: If successful, the approach could help survivors reduce risky substance use and improve long-term health outcomes.
How similar studies have gone: Prior short, structured screening and brief intervention methods have shown feasibility in various clinical settings, but this exact survivorship-focused integration is novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Followed in the ACT Clinic at St. Jude Children's Research Hospital * Greater than or equal to 15 years of age at time of evaluation * Able to speak and read English Exclusion Criteria: * Significant mental or cognitive impairment that would impact ability to complete surveys or participate in the brief intervention
Where it's running
-
St. Jude Children's Research Hospital
Memphis, Tennessee, United States Recruiting
Study contacts
- Principal investigator: Rachel Webster, PhD — St. Jude Children's Research Hospital
- Study coordinator: Rachel Webster, PhD
- Email: referralinfo@stjude.org
- Phone: 888-226-4343
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.