Prognosis of Infectious Endocarditis
Study of the Prognosis of Infectious Endocarditis (EPEI): Prospective and Retrospective Follow-up of a Cohort of Patients Hospitalized for Infectious Endocarditis
This study looks at how infectious endocarditis affects people with both natural and artificial heart valves to better understand the disease and improve treatment outcomes.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 645 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre Hospitalier Universitaire, Amiens Academic / other |
| Locations | 1 site (Amiens, Picardie) |
| Trial ID | NCT03211975 on ClinicalTrials.gov |
What this trial studies
This study investigates the prognosis of infectious endocarditis, focusing on both native valves and prosthetic valves. It aims to understand the evolution of this complex disease, which has seen changes in epidemiology and risk factors in recent years. The study will include patients diagnosed with infectious endocarditis according to Duke's criteria, confirmed through imaging or surgical specimens. By analyzing these cases, the study seeks to provide insights into the management and outcomes of this condition.
Who should consider this trial
Good fit: Ideal candidates for this study are patients diagnosed with infectious endocarditis who meet Duke's criteria.
Not a fit: Patients with infections that do not meet the Duke criteria for infectious endocarditis will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve the understanding and management of infectious endocarditis, potentially leading to better patient outcomes.
How similar studies have performed: While there have been studies on infectious endocarditis, this specific focus on the prognosis related to evolving risk factors is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * all patients with certain infectious endocarditis according to Duke's criteria, confirmed by the presence of evocative images on the transthoracic and / or transesophageal ultrasound or by the data collected on the surgical specimens. Exclusion Criteria: * Patients with an infection not meeting the Duke IE criteria.
Where this trial is running
Amiens, Picardie
- CHU Amiens Picardie — Amiens, Picardie, France (Recruiting)
Study contacts
- Study coordinator: Christophe TRIBOUILLOY, PhD
- Email: tribouilloy.christophe@chu-amiens.fr
- Phone: +33322455885
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.