Clinical trial Recruiting at 1 site Observational Ages 18 and up

Prognosis of Infectious Endocarditis

Official title: Study of the Prognosis of Infectious Endocarditis (EPEI): Prospective and Retrospective Follow-up of a Cohort of Patients Hospitalized for Infectious Endocarditis

Run by Centre Hospitalier Universitaire, Amiens · NCT03211975 · Data updated 2026-11-12

This study looks at how infectious endocarditis affects people with both natural and artificial heart valves to better understand the disease and improve treatment outcomes.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment645 (estimated)
SponsorCentre Hospitalier Universitaire, Amiens
Academic / other
Locations1 site (Amiens, Picardie)
StatusRecruiting
StartedFebruary 27, 2017
Main results expectedJune 2026
Study endsJune 2026
Registry record updatedJune 15, 2026
Trial IDNCT03211975 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients diagnosed with infectious endocarditis who meet Duke's criteria.

Probably not a fit

Patients with infections that do not meet the Duke criteria for infectious endocarditis will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the prognosis of infectious endocarditis, focusing on both native valves and prosthetic valves. It aims to understand the evolution of this complex disease, which has seen changes in epidemiology and risk factors in recent years. The study will include patients diagnosed with infectious endocarditis according to Duke's criteria, confirmed through imaging or surgical specimens. By analyzing these cases, the study seeks to provide insights into the management and outcomes of this condition.

Why it matters

Potential benefit: If successful, this study could improve the understanding and management of infectious endocarditis, potentially leading to better patient outcomes.

How similar studies have gone: While there have been studies on infectious endocarditis, this specific focus on the prognosis related to evolving risk factors is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* all patients with certain infectious endocarditis according to Duke's criteria, confirmed by the presence of evocative images on the transthoracic and / or transesophageal ultrasound or by the data collected on the surgical specimens.

Exclusion Criteria:

* Patients with an infection not meeting the Duke IE criteria.

Where it's running

  • CHU Amiens Picardie
    Amiens, Picardie, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.