Capacitive-resistive radiofrequency therapy for people with Parkinson's disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a randomized, within-subject crossover study in people with Parkinson's disease investigating the immediate and short-term effects of TECAR therapy applied to the lower limbs. Each participant receives four different treatment protocols in separate sessions with a 7-day washout between sessions, while continuing their usual medications. Outcomes include objective measures of lower-limb stiffness (MyotonPRO) and functional mobility (Timed Up and Go and 10-Meter Walk Test), along with range of motion and pain assessments. The study aims to determine which TECAR protocol provides the greatest improvement in muscle properties and gait during the pharmacological ON state. Safety and tolerability are also monitored throughout the sessions.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age between 55 and 90 years. Clinical diagnosis of idiopathic Parkinson's disease confirmed by a Neurology specialist.

Hoehn and Yahr stage II or III. Functional walking ability. Clinically relevant lower-limb rigidity in at least one leg, defined as a score ≥2 on item 3.3d (right lower limb) or 3.3e (left lower limb) of Part III of the Movement Disorder Society-Unified Parkinson's Disease Rating Scale (MDS-UPDRS).

Stable antiparkinsonian pharmacological treatment during the previous 4 weeks, with no planned changes during the intervention period.

Ability to understand and follow simple instructions, defined as a score \>24 on the validated Spanish version of the Mini-Mental State Examination (MMSE-MEC).

Provision of written informed consent.

Exclusion Criteria:

* Advanced Parkinson's disease, defined as Hoehn and Yahr stage \>III, with severe postural instability.

Other neurological or musculoskeletal conditions that could interfere with the assessment of lower-limb rigidity or gait.

Skin lesions, open wounds, or infection in the area where radiofrequency therapy will be applied.

Presence of a pacemaker, defibrillator, other implanted electronic device, or another contraindication to TECAR therapy, such as altered thermal sensitivity.

Lower-limb surgery within the previous 6 months.

Where it's running

• Asociación Parkinson Aragón
  Zaragoza, Zaragoza, Spain Recruiting

Study contacts

• Study coordinator: Paula Cordova-Alegre, PhD
• Email: pcordova@usj.es
• Phone: +34605245894

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.