RSV in young children in Ho Chi Minh City: how common and how much burden

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, multicenter, observational study enrolling children aged 0 to 24 months who present with acute respiratory infection symptoms. It uses continuous, convenience sampling across two epidemiological seasons (2026 and 2027) to capture RSV prevalence via nasopharyngeal swabs, alongside routine care. No change to standard treatment is made; data reflect real-world practice. The study aims to describe the epidemiology and clinical burden of RSV in this population in Vietnam's outpatient and inpatient settings. Enrollment continues until the target of 2,000 participants is reached across three sites over two seasons.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Children aged 0 to \<24 months (i.e., less than two years old).
* Children presenting with a diagnosis of acute respiratory infection (ARI), defined as an illness with one or more of the following symptoms: cough, rhinorrhea, sore throat, dyspnea (including wheezing, tachypnea, or apnea/increased work of breathing), sepsis (for infants aged \<6 months), and/or fever.
* Children residing in the lowest administrative division (Phường / Xã) in Vietnam that is designated for the specific study site (outpatient clinic or community hospital). As patients live in the same administrative district as the healthcare facility, this will facilitate follow-up and ensure that the study results are representative of the range of severity of ARI presenting to each specific study site.
* Parent or LAR provides written informed consent for their child's participation.

Exclusion Criteria:

* Children whose mothers received a maternal RSV vaccine during pregnancy or who have themselves received RSV-specific monoclonal antibodies (mAbs).
* Children with a known non-respiratory cause for hospitalization.
* Children with respiratory symptoms lasting over 14 days.
* Children hospitalized elsewhere within the preceding 4 days, excluding admission to the Emergency Department.
* Children already enrolled in another RSV study within the preceding 3 months.

Where it's running

• Di An Medical Center
  Ho Chi Minh City, Ho Chi Minh, Vietnam Recruiting
• Ba Ria General Hospital
  Ho Chi Minh City, Ho Chi Minh, Vietnam Not yet recruiting
• Le Van Thinh Hospital
  Ho Chi Minh City, Ho Chi Minh, Vietnam Not yet recruiting

Study contacts

• Study coordinator: Dung Van Do, MD, PhD
• Email: dungdv@tamri.vn
• Phone: 84918382253.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.