Robot-assisted reconstruction after surgery for rectal or anal cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study focuses on patients over 18 years old who have undergone robotic-assisted abdominoperineal resection for locally advanced rectal or anal cancer. It evaluates the effectiveness of reconstructing the pelvic floor and/or vagina using a rectus abdominis muscle flap. The study will track operative time, complications, wound healing, abdominal wall strength, and patient-reported outcomes related to quality of life and sexual health. Follow-up visits will occur at 1, 6, and 12 months post-surgery to assess these outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* patients with rectal or anal cancer
* scheduled for robot-assisted abdominoperineal resection
* reconstruction of pelvic floor and/or vagina with rectus abdominis muscle flap

Exclusion Criteria:

* patients not eligible for robot-assisted procedure
* rectus abdominis muscle not available for harvest
* the expected wound defect is not suitable for reconstruction with rectus abdominis muscle flap

Where it's running

• Oslo University Hospital, Radiumhospitalet
  Oslo, Norway Recruiting

Study contacts

• Principal investigator: Lars Frich, MD, PhD — Oslo University Hospital
• Study coordinator: Lars Frich, MD, PhD
• Email: lfrich@ous-hf.no
• Phone: 004722930000

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• New gel treatment for venous leg ulcers

  This study is testing a new gel treatment for people with stubborn venous leg ulcers to see if it helps them heal better than just the usual care.

  Recruiting at 5 sites Phase 3 TR Therapeutics · Jacksonville, Florida and 11 other locations · NCT06707103

• Comparing palatal wound healing in diabetic and non-diabetic patients

  This study is testing how well wounds in the mouth heal in people with diabetes compared to those without diabetes after surgery to fix gum issues.

  Recruiting at 2 sites Universidade Estadual Paulista Júlio de Mesquita Filho · São José dos Campos, São Paulo and 1 other locations · NCT06540690

• Using Oasis ECM to treat donor site wounds

  This study is testing if a new treatment called Oasis ECM can help heal donor site wounds better than regular wound care for people over 16 in the UK.

  Recruiting Cook Biotech Incorporated · Manchester, England · NCT04079348

• Characterization of the tumor microenvironment in locally advanced rectal cancer before and during neoadjuvant therapy

  This observational study tests how the tumor and immune cells change in locally advanced rectal cancer from baseline to during neoadjuvant therapy using advanced genomic and immune profiling.

  Recruiting Fujian Medical University Union Hospital · Fuzhou, Fujian · NCT07920770

• Prehabilitation with Resistance, Aerobic, or Both Before Colorectal Surgery

  Four pre-surgery exercise options (resistance, aerobic, both, or none) will be tested to see which best reduces complications after colorectal cancer surgery.

  Recruiting Semmelweis University · Budapest · NCT07896174

• Neoadjuvant therapy for locally advanced low rectal cancer: adding fruquintinib to short-course radiotherapy with tislelizumab and CAPOX

  This study tests whether adding fruquintinib to short-course radiotherapy plus tislelizumab and CAPOX before surgery helps people with locally advanced low rectal cancer achieve a better tumor response.

  Recruiting Phase 2 Ruijin Hospital · Shanghai, Shanghai Municipality · NCT07888309

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.