RISS vs SPSIP Block in Mastectomy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, double-blind trial compares two ultrasound-guided regional anesthesia techniques—RISS and SPSIP—for women undergoing unilateral modified radical mastectomy with axillary dissection. The study measures postoperative opioid use, pain scores, time to first rescue analgesia, sensory spread, recovery quality, and block-related complications. Adult participants are assigned to one block type before surgery and followed postoperatively under general anesthesia. The goal is to determine which block offers superior analgesia with a favorable safety profile in this surgical population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Female patients aged 18-75 years
* ASA physical status I-III
* Scheduled for elective unilateral modified radical mastectomy with axillary dissection under general anesthesia
* Provision of written informed consent

Exclusion Criteria:

* Anticoagulant therapy
* Bleeding diathesis
* Known allergy to local anesthetics or opioids
* Infection at the block application site or previous surgery in the block area
* Cognitive impairment preventing NRS assessment
* Pregnancy or lactation
* Chronic opioid use
* Severe hepatic or renal failure
* Refusal to participate in the study
* Technical inability to perform the block or failed block

Where it's running

• Bursa City Hospital
  Bursa, Nilüfer, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: Mürsel Ekinci, MD — Bursa City Hospital
• Study coordinator: Yusuf Alan, MD
• Email: dryusufalan@gmail.com
• Phone: +905396210977

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.