Clinical trial Recruiting at 1 site Observational Ages 18 and up

Right heart function after cardiac surgery: does respiratory acidosis matter?

Official title: Right Ventricular Function and Respiratory Acidosis After Cardiac Surgery

Run by Laval University · NCT07619274 · Data updated 2026-11-12

This study looks at whether respiratory acidosis after heart surgery affects how well the right side of the heart works in ICU patients.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment220 (estimated)
SponsorLaval University
Academic / other
Locations1 site (Québec, Quebec)
StatusRecruiting
StartedJuly 20, 2026
Main results expectedDecember 2026
Study endsJune 2027
Registry record updatedNovember 5, 2026
Trial IDNCT07619274 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Patients who were previously enrolled in and completed either NCT05886413 or NCT06826794 and have complete hemodynamic data and an arterial blood gas on ICU arrival.

Probably not a fit

Patients lacking the required hemodynamic measurements or arterial blood gas data on ICU arrival may not benefit from this analysis.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational analysis uses post hoc data from two previously approved studies to examine the association between early respiratory acidosis and right ventricular function after cardiac surgery. It stratifies patients by pH < 7.35 and PaCO2 > 45 mmHg on the first arterial blood gas in the ICU. Key hemodynamic measurements are required, including mean pulmonary pressures, central venous pressure, and cardiac output. No interventions are performed; the study observes existing data to identify potential links between acidosis and right heart performance.

Why it matters

Potential benefit: If associations are found, clinicians may better identify patients at risk for right heart dysfunction after surgery and tailor monitoring or management accordingly.

How similar studies have gone: There is precedent for post hoc analyses using existing datasets to explore cardio-pulmonary interactions after surgery, though the specific link with respiratory acidosis and RV function has limited prior direct evidence.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Previously included and complete study NCT05886413 or NCT06826794

Exclusion Criteria:

* Absence of one or more of the following hemodynamic measurements: systolic or diastolic pulmonary artery pressure, central venous pressure, cardiac output
* Absence of arterial blood gas on arrival to the intensive care unit

Where it's running

  • Institut universitaire de cardiologie et de pneumologie de Quebec - Universite Laval
    Québec, Quebec, Canada
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.