Revascularization of Calcified Coronary Arteries

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study will measure absolute coronary flow and pressure before and after percutaneous coronary intervention in calcified lesions to understand physiological changes. In addition, a machine learning model will be developed to predict the outcome of the intervention. Eligible participants are adults with moderate epicardial coronary disease who are candidates for PCI and intracoronary imaging, with de novo lesions. Exclusions include severely reduced kidney function, recent acute coronary syndrome, inability to consent, left main disease, or a plan for bypass surgery. The study is led by Aalborg University Hospital with no additional collaborators and is conducted at Aalborg University Hospital in Aalborg, Denmark.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age \> 18 years
* Moderate (40-90 %) epicardial disease
* Vessel suitable for PCI and intracoronary imaging
* De novo-lesions

Exclusion Criteria:

* eGFR \< 40ml/min
* ACS \< 48 hours
* Patient without ability to provide informed consent
* Patient with left main stenosis
* Indication for coronary artery bypass grafting

Where it's running

• Aalborg University Hospital
  Aalborg, Denmark Recruiting

Study contacts

• Study coordinator: Ashkan Eftekhari, MD PhD
• Email: asef@rn.dk
• Phone: +4597664465

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.