Research on gut inflammation in pediatric patients with inflammatory bowel diseases

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to collect long-term clinical data and biological samples from pediatric patients diagnosed with inflammatory bowel diseases (IBD), including Crohn's disease and ulcerative colitis. It will also include a control group of pediatric patients with disorders of brain-gut interactions who do not have detectable gut inflammation. Participants will undergo standard clinical evaluations, during which blood, stool, and tissue samples will be collected as needed. Additionally, urine samples will be collected specifically for research purposes during clinical visits.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Suspected diagnosis of CD (Crohn's Disease), UC (Ulcerative Colitis) or Indeterminate colitis (IC)

Exclusion Criteria:

* Evidence of Other Complicating Medical Issues:
* Other serious medical conditions, such as neurological, liver, kidney, or systemic disease
* Pregnancy
* Tobacco, alcohol, or illicit drug abuse

Where it's running

• Seattle Children's Hospital
  Seattle, Washington, United States Recruiting

Study contacts

• Principal investigator: Betty (Hengqi) Zheng, MD — Seattle Children's Hospital, University of Washington
• Study coordinator: Mason E Nuding, BS
• Email: mason.nuding@seattlechildrens.org
• Phone: 206-987-0055

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Self-management program to improve health in inflammatory bowel disease

  A digital self-management program is being tested to see if it helps people with inflammatory bowel disease feel better and manage their symptoms alongside standard care.

  Recruiting University of Michigan · Ann Arbor, Michigan · NCT07456566

• Observational study comparing inflammatory markers in IBD and non-IBD participants

  This study is trying to see how inflammation levels in people with Crohn's Disease and Ulcerative Colitis compare to those without these conditions when they start new treatments.

  Recruiting University of Nottingham · Nottingham, Nottinghamshire · NCT06956703

• Evaluating robotic surgery for inflammatory bowel disease

  This study is testing if robotic surgery can be a good option for adults with inflammatory bowel disease, like Crohn's or ulcerative colitis, compared to traditional surgery methods.

  Recruiting at 6 sites University Hospitals Coventry and Warwickshire NHS Trust · Coventry, West Midlands and 5 other locations · NCT06579443

• How nutrition and body composition relate to outcomes in people with IBD

  This study will see if nutrition and muscle mass affect outcomes in people with Crohn's disease or ulcerative colitis who are starting advanced medicines or having IBD-related surgery.

  Recruiting Barts & The London NHS Trust · London · NCT06550310

• Switching to subcutaneous infliximab for IBD treatment

  This study is testing if switching people with inflammatory bowel disease from an intravenous form of infliximab to a subcutaneous version, given weekly or bi-weekly, can lead to better health results.

  Recruiting at 14 sites Phase 4 Belgian Inflammatory Bowel Disease Research and Development (BIRD) VZW · Ghent, Oost-Vlaanderen and 14 other locations · NCT06113913

• Analyzing genetic factors in inflammatory bowel disease across different populations

  This study is trying to find out how genes and the environment affect inflammatory bowel disease by looking at samples from people with the condition and healthy individuals.

  Recruiting Mount Sinai Hospital, Canada · Toronto, Ontario · NCT06042387

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.