Research on gut inflammation in pediatric patients with inflammatory bowel diseases
Seattle Spatial Transcriptomic Research in Inflammatory Bowel Disease Evaluation
Seattle Children's Hospital · NCT06315179
This study is trying to learn more about gut inflammation in kids with inflammatory bowel diseases by collecting health information and samples from them and comparing it to kids who have different gut issues but no inflammation.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 6 Years to 21 Years |
| Sex | All |
| Sponsor | Seattle Children's Hospital (other) |
| Locations | 1 site (Seattle, Washington) |
| Trial ID | NCT06315179 on ClinicalTrials.gov |
What this trial studies
This observational study aims to collect long-term clinical data and biological samples from pediatric patients diagnosed with inflammatory bowel diseases (IBD), including Crohn's disease and ulcerative colitis. It will also include a control group of pediatric patients with disorders of brain-gut interactions who do not have detectable gut inflammation. Participants will undergo standard clinical evaluations, during which blood, stool, and tissue samples will be collected as needed. Additionally, urine samples will be collected specifically for research purposes during clinical visits.
Who should consider this trial
Good fit: Ideal candidates for this study are pediatric patients suspected of having Crohn's disease, ulcerative colitis, or indeterminate colitis.
Not a fit: Patients with other serious medical conditions or those who are pregnant may not benefit from this study.
Why it matters
Potential benefit: If successful, this research could enhance understanding of inflammatory bowel diseases and improve treatment strategies for affected pediatric patients.
How similar studies have performed: Other studies have shown promise in understanding inflammatory bowel diseases through similar observational approaches, indicating potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Suspected diagnosis of CD (Crohn's Disease), UC (Ulcerative Colitis) or Indeterminate colitis (IC) Exclusion Criteria: * Evidence of Other Complicating Medical Issues: * Other serious medical conditions, such as neurological, liver, kidney, or systemic disease * Pregnancy * Tobacco, alcohol, or illicit drug abuse
Where this trial is running
Seattle, Washington
- Seattle Children's Hospital — Seattle, Washington, United States (RECRUITING)
Study contacts
- Principal investigator: Betty (Hengqi) Zheng, MD — Seattle Children's Hospital, University of Washington
- Study coordinator: Mason E Nuding, BS
- Email: mason.nuding@seattlechildrens.org
- Phone: 206-987-0055
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis, Indeterminate Colitis, Functional Abdominal Pain Syndrome, Functional Bowel Disorder, Esophageal Diseases, Gastroduodenal Disorder