Remifentanil With or Without Lidocaine for Extubation After Thyroid Surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

In this randomized, double-blind trial, 60 adults undergoing elective thyroidectomy will receive remifentanil during emergence from anesthesia, with half also receiving intravenous lidocaine before extubation. The study compares coughing during tracheal extubation and also looks at cough severity, vital signs, airway events, sore throat, hoarseness, nausea and vomiting, sedation, and recovery times. Outcomes will indicate if lidocaine plus remifentanil provides a smoother, safer extubation than remifentanil alone. The trial is parallel-group and conducted at Pamukkale University Hospitals. Patients meet standard anesthesia criteria and will be assessed for eligibility and safety throughout.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 to 65 years American Society of Anesthesiologists (ASA) physical status I or II Scheduled for elective thyroidectomy under general anesthesia Body mass index (BMI) \<35 kg/m² Able to provide written informed consent

Exclusion Criteria:

* History of chronic respiratory disease, including asthma or chronic obstructive pulmonary disease (COPD) Active upper or lower respiratory tract infection Known airway abnormality or anticipated difficult airway Known allergy or hypersensitivity to lidocaine Planned postoperative intubation or extubation in the intensive care unit Refusal to participate or withdrawal of consent

Where it's running

• Pamukkale University Hospitals
  Denizli, Turkey (Türkiye) Recruiting

Study contacts

• Principal investigator: saadet nur YALCIN SATICI — Pamukkale University
• Study coordinator: saadet nur YALCIN SATICI
• Email: yalcinsaadetnur@gmail.com
• Phone: +905066474672

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.