Reliability of Two-Stage Multiple-Repetition-Maximum Tests to Estimate 1-RM in People with Heart Disease and Risk Factors
Official title: Agreement of the Estimated 1-Repetition-Maximum Between Two Multiple-Repetition-Maximum Tests With Different Weight in Patients With Cardiovascular Disease or Risk Factors
Run by Technical University of Munich · NCT06796582 · Data updated 2026-11-12
This study checks how well different formulas estimate the 1-RM from two submaximal tests in adults with heart disease or risk factors.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 50 Years and up |
| Sex | All |
| Enrollment | 50 (estimated) |
| Sponsor | Technical University of Munich Academic / other |
| Locations | 1 site (München) |
| Status | Recruiting |
| Started | July 14, 2025 |
| Main results expected | February 2027 |
| Study ends | February 2027 |
| Registry record updated | October 22, 2026 |
| Trial ID | NCT06796582 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 50 years and older with heart failure, coronary heart disease, atrial fibrillation, arterial hypertension, or type 2 diabetes, who are clinically stable and cleared for resistance testing.
✕Probably not a fit
Individuals with recent instability, acute infection, or significant musculoskeletal or neurologic conditions limiting testing may not benefit from these estimation methods.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study investigates whether estimating the 1-RM from multiple-repetition tests is reliable when two submaximal tests use different weights. The goal is to see if these estimates agree across the two testing sessions in adults aged 50 and older with cardiovascular disease or risk factors. The results could help safer and accessible resistance training prescription for this population. No interventions are described; the focus is on measurement reliability and formula performance. Findings may inform practical guidelines for muscle-strength assessments in cardiometabolic patients.
Why it matters
Potential benefit: If reliable, the estimation methods could allow safer, lower-load strength testing to guide resistance training in people with cardiovascular disease or risk factors.
How similar studies have gone: Prior work on 1-RM estimation primarily in healthy individuals; reliability in cardiovascular populations remains uncertain and this study tests that gap.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 50 years * At least one of the following cardiovascular diseases / risk factors: * Heart failure * Coronary heart disease * Atrial fibrillation * Arterial hypertension * Type 2 diabetes mellitus * Clinically stable for ≥ 4 weeks * Medical clearance to perform resistance training / strength testing * Signed written informed consent Exclusion Criteria: * Pregnancy * Acute infection * Chronic joint inflammation * Knee, hip, ankle, wrist, elbow or shoulder pain * Known osteoporosis (T-value ≤ -2.5) * Uncontrolled hypertension (≥160 mmHG systolic / ≥100 mmHG diastolic) * Known cerebral or thoracic aneurysm
Where it's running
-
Department for Preventive Sports Medicine and Sports Cardiology, TUM Klinikum Rechts der Isar, Technical University of Munich
München, Germany Recruiting
Study contacts
- Principal investigator: Stephan Mueller, Dr rer nat — Technical University of Munich, Department for Preventive Sports Medicine and Sports Cardiology
- Study coordinator: Stephan Mueller, Dr rer nat
- Email: stephan.mueller@mri.tum.de
- Phone: +49 (0)89 289 24494
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.