Registry on coronary function testing in Belgium
A Prospective Multicenter Registry on Coronary Function Tests, Organized by the Belgian Working Group on Coronary Microcirculation/Belgian Microcirculation Registry.
This study looks at how often doctors in Belgium use tests to check heart blood flow and related issues in patients, while also gathering information about their symptoms and quality of life.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 650 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University Hospital, Antwerp Academic / other |
| Locations | 13 sites (Deurne, Antwerp and 12 other locations) |
| Trial ID | NCT06089031 on ClinicalTrials.gov |
What this trial studies
This prospective, multicenter registry aims to document the real-world application of coronary function tests in Belgium, focusing on bolus thermodilution measurements and invasive vasoreactivity tests. It will assess the frequency of these tests, their indications, and the prevalence of coronary microvascular dysfunction and vasospasm among patients. Data will be collected from medical files, including cardiovascular risk factors and follow-up information, with optional questionnaires on symptoms and quality of life. The study does not require specific visits, making it a practical observational approach.
Who should consider this trial
Good fit: Ideal candidates are patients scheduled for coronary function tests who can provide informed consent.
Not a fit: Patients who are pregnant or unable to provide consent, as well as those participating in other investigational trials, may not benefit from this study.
Why it matters
Potential benefit: If successful, this registry could enhance understanding of coronary function testing and improve patient management for those with coronary microvascular dysfunction and vasospasm.
How similar studies have performed: While similar observational studies have been conducted, this registry focuses specifically on the real-world application of coronary function tests in Belgium, making it a novel approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient scheduled for coronary function test, comprising of intracoronary bolus thermodilution measurements of microvascular function, and/or intracoronary vasoreactivity tests with acetylcholine. * Subject understands the study requirements and provides written informed consent. Exclusion Criteria: * Subject is participating in another investigational clinical trial that may cause non-compliance with the protocol or confound data interpretation. * Subject intends to participate in another investigational clinical trial that may cause non-compliance with the protocol or confound data interpretation. * Documented or suspected pregnancy. * Inability to provide written informed consent.
Where this trial is running
Deurne, Antwerp and 12 other locations
- AZ Monica — Deurne, Antwerp, Belgium (Recruiting)
- AZ Sint-Maarten — Mechelen, Antwerp, Belgium (Recruiting)
- Jessa Hasselt — Hasselt, Limburg, Belgium (Recruiting)
- OLV Aalst — Aalst, Belgium (Recruiting)
- Ziekenhuis aan de Stroom (ZAS) — Antwerp, Belgium (Recruiting)
- University Hospital Antwerp — Antwerp, Belgium (Recruiting)
- AZ Sint-Jan Brugge — Bruges, Belgium (Recruiting)
- AZ Jan Yperman — Ieper, Belgium (Recruiting)
- AZ Groeninge — Kortrijk, Belgium (Recruiting)
- UZ Leuven — Leuven, Belgium (Recruiting)
- CHC Montlégia Liège — Liège, Belgium (Recruiting)
- CHR Citadelle Liège — Liège, Belgium (Recruiting)
- AZ Delta — Roeselare, Belgium (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.