Registry of patients with angina undergoing coronary physiology testing
Southeastern Europe Microcirculation Registry
Institute for Cardiovascular Diseases Dedinje · NCT06393478
This study collects information from adults with angina to see how well different tests for heart issues work and what happens to patients over time.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 900 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Institute for Cardiovascular Diseases Dedinje (other) |
| Locations | 10 sites (Rijeka and 9 other locations) |
| Trial ID | NCT06393478 on ClinicalTrials.gov |
What this trial studies
This registry collects data from adults with angina symptoms who are referred for coronary artery disease evaluation and undergo invasive physiology testing. It aims to assess the practice of patient selection, cardiovascular outcomes, and additional procedures following comprehensive coronary physiology evaluations. Data collected includes demographic information, cardiovascular risk factors, and results from various tests related to coronary microvascular function. Follow-up visits will track major adverse cardiovascular events over a period of up to five years.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 years old experiencing angina symptoms who are referred for coronary artery disease evaluation.
Not a fit: Patients under 18, pregnant or nursing women, and those without coronary physiology measurements will not benefit from this registry.
Why it matters
Potential benefit: If successful, this registry could improve the understanding and management of coronary microvascular dysfunction in patients with angina.
How similar studies have performed: Other studies focusing on coronary physiology testing have shown promising results, indicating that this approach may be beneficial.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults of both sexes older than 18 years * Angina symptoms or angina equivalent * Referred to Cath lab for evaluation of CAD * Invasive physiology testing performed (microcirculation testing +/- vasospasm testing) using Coroflow Coroventis Cardiovascular system (Abbott Vascular, Abbott Park, IL, USA) Exclusion Criteria: * Persons under the age of 18 * Pregnant of nursing * No coronary physiology measurements performed
Where this trial is running
Rijeka and 9 other locations
- CHC Rijeka — Rijeka, Croatia (NOT_YET_RECRUITING)
- KBC Zagreb — Zagreb, Croatia (NOT_YET_RECRUITING)
- MITERA General Hospital — Athens, Greece (RECRUITING)
- Hippokration Hospital — Athens, Greece (RECRUITING)
- Heraklion University Hospital — Heraklion, Greece (RECRUITING)
- University Hospital of Patras — Pátrai, Greece (RECRUITING)
- Tel Aviv Sourasky MC — Tel Aviv, Israel (NOT_YET_RECRUITING)
- Institute for cardiovascular diseases Dedinje — Belgrade, Serbia (RECRUITING)
- Institute for cardiovascular diseases Vojvodine — Novi Sad, Serbia (RECRUITING)
- UMC Ljubljana — Ljubljana, Slovenia (NOT_YET_RECRUITING)
Study contacts
- Study coordinator: Ivan S Ilić, MD, PhD
- Email: ivan1ilic@yahoo.com
- Phone: +381641374455
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Angina, Microvascular, Coronary Microvascular Dysfunction, Coronary Artery Disease, microvascular angina, thermodilution, coronary flow reserve