Registry of patients with angina undergoing coronary physiology testing
Official title: Southeastern Europe Microcirculation Registry
Run by Institute for Cardiovascular Diseases Dedinje · NCT06393478 · Data updated 2026-11-12
This study collects information from adults with angina to see how well different tests for heart issues work and what happens to patients over time.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 900 (estimated) |
| Sponsor | Institute for Cardiovascular Diseases Dedinje Academic / other |
| Locations | 10 sites (Rijeka and 9 other locations) |
| Status | Recruiting |
| Started | March 1, 2024 |
| Main results expected | March 1, 2029 |
| Study ends | March 1, 2034 |
| Registry record updated | May 14, 2024 |
| Trial ID | NCT06393478 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults over 18 years old experiencing angina symptoms who are referred for coronary artery disease evaluation.
✕Probably not a fit
Patients under 18, pregnant or nursing women, and those without coronary physiology measurements will not benefit from this registry.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This registry collects data from adults with angina symptoms who are referred for coronary artery disease evaluation and undergo invasive physiology testing. It aims to assess the practice of patient selection, cardiovascular outcomes, and additional procedures following comprehensive coronary physiology evaluations. Data collected includes demographic information, cardiovascular risk factors, and results from various tests related to coronary microvascular function. Follow-up visits will track major adverse cardiovascular events over a period of up to five years.
Why it matters
Potential benefit: If successful, this registry could improve the understanding and management of coronary microvascular dysfunction in patients with angina.
How similar studies have gone: Other studies focusing on coronary physiology testing have shown promising results, indicating that this approach may be beneficial.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults of both sexes older than 18 years * Angina symptoms or angina equivalent * Referred to Cath lab for evaluation of CAD * Invasive physiology testing performed (microcirculation testing +/- vasospasm testing) using Coroflow Coroventis Cardiovascular system (Abbott Vascular, Abbott Park, IL, USA) Exclusion Criteria: * Persons under the age of 18 * Pregnant of nursing * No coronary physiology measurements performed
Where it's running
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MITERA General Hospital
Athens, Greece Recruiting -
Hippokration Hospital
Athens, Greece Recruiting -
Heraklion University Hospital
Heraklion, Greece Recruiting -
University Hospital of Patras
Pátrai, Greece Recruiting -
Institute for cardiovascular diseases Dedinje
Belgrade, Serbia Recruiting -
Institute for cardiovascular diseases Vojvodine
Novi Sad, Serbia Recruiting
Show 4 more locations
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CHC Rijeka
Rijeka, Croatia Not yet recruiting -
KBC Zagreb
Zagreb, Croatia Not yet recruiting -
Tel Aviv Sourasky MC
Tel Aviv, Israel Not yet recruiting -
UMC Ljubljana
Ljubljana, Slovenia Not yet recruiting
Study contacts
- Study coordinator: Ivan S Ilić, MD, PhD
- Email: ivan1ilic@yahoo.com
- Phone: +381641374455
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.