Clinical trial Recruiting at 6 sites Observational Ages 18 and up

Registry of patients with angina undergoing coronary physiology testing

Official title: Southeastern Europe Microcirculation Registry

Run by Institute for Cardiovascular Diseases Dedinje · NCT06393478 · Data updated 2026-11-12

This study collects information from adults with angina to see how well different tests for heart issues work and what happens to patients over time.

More Coronary Microvascular Dysfunction trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment900 (estimated)
SponsorInstitute for Cardiovascular Diseases Dedinje
Academic / other
Locations10 sites (Rijeka and 9 other locations)
StatusRecruiting
StartedMarch 1, 2024
Main results expectedMarch 1, 2029
Study endsMarch 1, 2034
Registry record updatedMay 14, 2024
Trial IDNCT06393478 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults over 18 years old experiencing angina symptoms who are referred for coronary artery disease evaluation.

Probably not a fit

Patients under 18, pregnant or nursing women, and those without coronary physiology measurements will not benefit from this registry.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This registry collects data from adults with angina symptoms who are referred for coronary artery disease evaluation and undergo invasive physiology testing. It aims to assess the practice of patient selection, cardiovascular outcomes, and additional procedures following comprehensive coronary physiology evaluations. Data collected includes demographic information, cardiovascular risk factors, and results from various tests related to coronary microvascular function. Follow-up visits will track major adverse cardiovascular events over a period of up to five years.

Why it matters

Potential benefit: If successful, this registry could improve the understanding and management of coronary microvascular dysfunction in patients with angina.

How similar studies have gone: Other studies focusing on coronary physiology testing have shown promising results, indicating that this approach may be beneficial.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults of both sexes older than 18 years
* Angina symptoms or angina equivalent
* Referred to Cath lab for evaluation of CAD
* Invasive physiology testing performed (microcirculation testing +/- vasospasm testing) using Coroflow Coroventis Cardiovascular system (Abbott Vascular, Abbott Park, IL, USA)

Exclusion Criteria:

* Persons under the age of 18
* Pregnant of nursing
* No coronary physiology measurements performed

Where it's running

  • MITERA General Hospital
    Athens, Greece
    Recruiting
  • Hippokration Hospital
    Athens, Greece
    Recruiting
  • Heraklion University Hospital
    Heraklion, Greece
    Recruiting
  • University Hospital of Patras
    Pátrai, Greece
    Recruiting
  • Institute for cardiovascular diseases Dedinje
    Belgrade, Serbia
    Recruiting
  • Institute for cardiovascular diseases Vojvodine
    Novi Sad, Serbia
    Recruiting
Show 4 more locations
  • CHC Rijeka
    Rijeka, Croatia
    Not yet recruiting
  • KBC Zagreb
    Zagreb, Croatia
    Not yet recruiting
  • Tel Aviv Sourasky MC
    Tel Aviv, Israel
    Not yet recruiting
  • UMC Ljubljana
    Ljubljana, Slovenia
    Not yet recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.