Registry of inflammatory bowel disease patients in Zimbabwe
Registry to Study the Incidence, Phenotype, Risk Factors and Clinical Course of Inflammatory Bowel Disease in Zimbabwe
This study is creating a registry of people with inflammatory bowel disease in Zimbabwe to collect information about their condition and see what factors might contribute to it.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Sex | All |
| Sponsor | University of Zimbabwe Academic / other |
| Locations | 1 site (Harare) |
| Trial ID | NCT04178408 on ClinicalTrials.gov |
What this trial studies
This study aims to establish a prospective registry of patients diagnosed with inflammatory bowel disease at Parirenyatwa Hospital in Harare, Zimbabwe. It will collect data on disease characteristics, management, and risk factors through questionnaires and biobanking of stool specimens and DNA. The registry will include confirmed cases of inflammatory bowel disease and their controls, which consist of relatives and neighborhood individuals. Data will be analyzed to understand the incidence and risk factors associated with inflammatory bowel disease in this population.
Who should consider this trial
Good fit: Ideal candidates include adults with confirmed inflammatory bowel disease who have had the condition for at least three months.
Not a fit: Patients under 18 years old or those with suspected inflammatory bowel disease will not benefit from this study.
Why it matters
Potential benefit: If successful, this registry could enhance understanding of inflammatory bowel diseases in Sub-Saharan Africa and improve patient management.
How similar studies have performed: While similar registries have been established in other regions, this specific approach in a Sub-Saharan African context is novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Cases 1. Any patient with confirmed inflammatory bowel disease 2. Onset of disease ≥3 months ago. * Controls 1. Age ≥ 18 years (NB - cases younger than 18 will be excluded from case-control analysis 2. One sibling or cousin (2nd degree) and one neighbourhood control. Exclusion Criteria: * Cases 1\. None * Controls 1. Suspected inflammatory bowel disease 2. Unexplained gastrointestinal symptoms including diarrhoea, vomiting, chronic abdominal pain, weight loss, rectal bleeding, and recent change in bowel habit. 3. Previous unexplained gastrointestinal surgery
Where this trial is running
Harare
- Parirenyatwa Hospital — Harare, Zimbabwe (Recruiting)
Study contacts
- Principal investigator: Leolin Katsidzira, MD — University of Zimbabwe
- Study coordinator: Leolin Katsidzira, MD
- Email: lkatsidzira@hotmail.com
- Phone: +263 77 2377 416
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.