Analysis of surgical treatments for bone metastases in the proximal femur
Complications, Implant Survival and Functional Results After Surgical Treatment of Bone Metastases of Proximal Femur With Intramedullary Nail or Prosthetic Reconstruction
This study looks at how well different surgical treatments for bone metastases in the upper thigh bone work for patients who have had fractures.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 600 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Istituto Ortopedico Rizzoli Academic / other |
| Locations | 1 site (Bologna, Emilia-Romagna) |
| Trial ID | NCT06918860 on ClinicalTrials.gov |
What this trial studies
This study collects data from patients who underwent surgical treatment for impending or pathological fractures of the proximal femur due to bone metastases between 2000 and 2023. It focuses on analyzing outcomes from various surgical interventions, including intramedullary nails and prosthetic reconstructions. The investigators will review medical records, radiological imaging, and histological data to assess the effectiveness of these treatments. Approximately 600 patients are expected to be included in the analysis.
Who should consider this trial
Good fit: Ideal candidates are adult patients aged 18 and older who have undergone surgery for fractures due to bone metastases of the proximal femur.
Not a fit: Patients with fractures due to primary bone tumors will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve treatment strategies for patients with bone metastases, leading to better surgical outcomes.
How similar studies have performed: Other studies have shown success with similar surgical approaches for bone metastases, indicating a potential for meaningful insights from this analysis.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male and female adult patients surgically treated between 01/01/2000 and 31/12/2023 in Rizzoli Orthopaedic Institute and in Massachusetts General Hospital. * Age ≥18 y (at the time of surgery) * Patients with impending or pathological fracture due to bone metastases of the proximal femur (head/neck, intertrochanteric, subtrochanteric area). * Patients who underwent either IMN or THA or HHA or Mega or MegaTHA. * Patients with available clinical and imaging data. Exclusion Criteria: * Patients with pathological or impending fracture of proximal femur due to primary bone tumor.
Where this trial is running
Bologna, Emilia-Romagna
- Irccs Istituto Ortopedico Rizzoli — Bologna, Emilia-Romagna, Italy (Recruiting)
Study contacts
- Study coordinator: Costantino Errani, MD
- Email: costantino.errani@ior.it
- Phone: 0516366
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.