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Registry for patients with cardiogenic shock

Cardiogenic Shock Working Group Registry

Observational Tufts Medical Center · NCT04682483

This study is gathering health information from patients with cardiogenic shock at different hospitals to help improve treatment and understanding of this serious condition.

Quick facts

Study typeObservational
Enrollment5000 (estimated)
Ages18 Years and up
SexAll
SponsorTufts Medical Center Academic / other
Locations16 sites (Weston, Florida and 15 other locations)
Trial IDNCT04682483 on ClinicalTrials.gov

What this trial studies

The Cardiogenic Shock Working Group is a multicenter registry that collects de-identified clinical data from patients experiencing cardiogenic shock across various institutions in the United States. This registry aims to centralize data for better analysis of clinical outcomes related to cardiogenic shock, which currently lacks a comprehensive database. It includes both retrospective data collected during hospital stays and prospective data for long-term outcomes. The goal is to enhance understanding and treatment of cardiogenic shock through collaborative research.

Who should consider this trial

Good fit: Ideal candidates for this registry are patients diagnosed with cardiogenic shock who meet specific clinical criteria.

Not a fit: Patients who do not have cardiogenic shock or those who do not meet the defined clinical criteria will not benefit from this registry.

Why it matters

Potential benefit: If successful, this registry could lead to improved treatment strategies and outcomes for patients suffering from cardiogenic shock.

How similar studies have performed: Other studies have shown success with similar registry approaches, indicating the potential for valuable insights in managing cardiogenic shock.

Eligibility criteria

Show full inclusion / exclusion criteria 
Inclusion Criteria:

* Patients must have cardiogenic shock.

Cardiogenic shock is defined by at least one of the two categories below:

1. At least 2 of the following concurrently at any point during the index hospitalization:

   * Cardiac Index \< 2.2
   * PAPI \< 1.0
   * Cardiac Power Output ≤ 0.6
   * MAP \< 60mmHg or a \>30mmHg drop in MAP from baseline
   * SBP \< 90mmHg or a \>30mmHg drop in SBP from baseline
   * Pulse \> 100
2. Require at least one acute mechanical circulatory support device, vasopressor or inotrope to maintain values above the above target.

Post-cardiotomy patients must meet the inclusion criteria 72 hours after their surgery to be included in this registry.

Where this trial is running

Weston, Florida and 15 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
View on ClinicalTrials.gov → Find more trials like this →
Conditions Cardiogenic Shockmechanical circulatory supporthemodynamicsheart failureacute myocardial infarctionregistrycritical careclinical outcomes research
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.