Registry for patients with anomalous aortic origin of coronary arteries

EUROAAOCA Registry

Observational University of Padova · NCT06089902

This study is collecting information from patients with a rare heart condition called anomalous aortic origin of coronary arteries to see how different treatments work and improve care for everyone.

Quick facts

Study typeObservational
Enrollment500 (estimated)
SexAll
SponsorUniversity of Padova Academic / other
Locations2 sites (Padova, PD and 1 other locations)
Trial IDNCT06089902 on ClinicalTrials.gov

What this trial studies

The European Registry for Anomalous Aortic Origin of Coronary Arteries (EURO-AAOCA) aims to collect and analyze data on patients diagnosed with AAOCA to improve management strategies across different medical centers. This observational study will gather baseline demographic information, symptoms, and procedural details from participating centers, ensuring patient anonymity. The registry will help identify variations in treatment approaches and outcomes, ultimately guiding better clinical practices for this rare congenital heart defect.

Who should consider this trial

Good fit: Ideal candidates for this registry are patients diagnosed with AAOCA, whether they are referred for surgical intervention or medical follow-up.

Not a fit: Patients with isolated high-coronary take-off, anomalous origin of a circumflex from the right coronary artery, or major congenital heart diseases may not benefit from this registry.

Why it matters

Potential benefit: If successful, this registry could lead to improved management and outcomes for patients with anomalous aortic origin of coronary arteries.

How similar studies have performed: Other registries focusing on congenital heart defects have shown success in improving patient management and outcomes, suggesting a positive outlook for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All patients with a diagnosis of AAOCA (either referred to surgery or to medical follow-up )

Exclusion Criteria:

* isolated high-coronary take-off (≥ 5mm above sino-tubular junction), anomalous origin of a circumflex from the right coronary artery, anomalous course with a normal origin, and association to major congenital heart disease (i.e. Tetralogy of Fallot, transposition of the great arteries, anomalous origin of a coronary from the pulmonary artery).

Where this trial is running

Padova, PD and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Congenital Heart DiseaseCoronary Artery AnomalySudden Cardiac DeathSurgical Procedure, UnspecifiedDiagnosisArrhythmiaHeart Defects, CongenitalAdult Children
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.