Registry for patients undergoing Transcatheter Aortic Valve Replacement

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational registry aims to evaluate the safety and efficacy of Transcatheter Aortic Valve Implantation (TAVI) in patients with symptomatic severe aortic stenosis. It will collect clinical, procedural, and echocardiographic data to assess the clinical outcomes of the TAVI procedure. The study is conducted at the Federico II University in Naples and focuses on patients deemed suitable for TAVI by a multidisciplinary team. The findings will contribute to understanding the impact of TAVI on patient health and outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Patients with symptomatic severe AS or degenerated bioprosthetic aortic valve and suitable for TAVI according to Heart Team evaluation;
2. Ability to provide informed consent.

Exclusion Criteria:

1. Contraindications to TAVI: e.g. evidence of intracardiac mass, thrombus or vegetation, endocarditis;
2. Poor adherence to scheduled follow-up;
3. Unable to understand and follow study-related instructions.

Where it's running

• Federico II University of Naples
  Naples, Italy Recruiting

Study contacts

• Principal investigator: Giovanni Esposito, MD, PhD — Federico II University
• Study coordinator: Giovanni Esposito, MD, PhD
• Email: espogiov@unina.it
• Phone: +390817463075

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• How TAVI affects gut bacteria in people with severe aortic stenosis

  This will test whether transcatheter aortic valve implantation (TAVI) changes the gut microbiota and related blood markers in people with severe aortic stenosis.

  Recruiting Hippocration General Hospital · Athens · NCT07052071

• Using SMART watches to monitor patients after heart valve replacement

  This study tests if using a HUAWEI smartwatch to track heart rate, oxygen levels, and activity can help patients who have had heart valve replacement spot problems early and recover better.

  Recruiting Second Affiliated Hospital, Zhejiang University, School of Medicine · Hangzhou, Zhejiang · NCT04454177

• Exercise and nutrition support before and after TAVI for older adults with aortic stenosis

  This trial tests whether a personalized exercise program plus protein and iron supplements before and after a transcatheter valve replacement can help older adults with aortic stenosis recover better than standard care.

  Recruiting University Hospital of Ferrara · Ferrara, FE · NCT07895719

• SYMmetric Valve expansion to reduce hypoattenuated leaflet thickening after balloon-expandable TAVI

  This trial tests whether the Double-TAP post-dilatation strategy can reduce HALT and improve valve function in patients 70 or older undergoing balloon-expandable TAVI.

  Recruiting Erasmus Medical Center · Düsseldorf and 4 other locations · NCT07872020

• Association Between Aortic Valve Area Changes and Pulmonary Congestion After TAVI

  This study tests whether improvements in aortic valve opening after TAVI relate to reductions in lung congestion measured by ultrasound in adults with severe aortic stenosis.

  Recruiting Istanbul University - Cerrahpasa · Istanbul, Istanbul · NCT07794436

• Systematic 14-day ambulatory heart monitoring after TAVI

  After TAVI, patients with certain heart conduction abnormalities will try 14 days of wearable ECG monitoring to see if it lowers the chances of sudden death, symptomatic heart rhythm problems, or stroke within a year compared to standard follow-up.

  Recruiting Institut universitaire de cardiologie et de pneumologie de Québec, University Laval · Québec, Quebec · NCT07739316

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.