Registry for Familial Colorectal Cancer in Hispanics
Familial Colorectal Cancer In Puerto Rico: A Feasibility Study
This study is trying to create a registry of families affected by colorectal cancer in Puerto Rico to learn more about the genetic and environmental factors that may increase the risk for Hispanic people.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 5000 (estimated) |
| Ages | 15 Years and up |
| Sex | All |
| Sponsor | University of Puerto Rico Academic / other |
| Locations | 2 sites (San Juan and 1 other locations) |
| Trial ID | NCT00927680 on ClinicalTrials.gov |
What this trial studies
This observational study aims to establish a familial colorectal cancer registry in Puerto Rico to better understand the genetic epidemiology of colorectal cancer among Hispanic populations. The study will recruit approximately 300 colorectal cancer probands from two geographical areas in Puerto Rico and gather detailed family history, tumor, blood, and medical information. By focusing on familial cases, the research seeks to identify genetic and environmental risk factors, paving the way for future genetic studies and potential interventions.
Who should consider this trial
Good fit: Ideal candidates include individuals aged 15 and older with colon polyps or colon cancer, as well as control subjects aged 21 and older with no malignant conditions in the colon or rectum.
Not a fit: Patients under 15 years old or those unable to provide consent will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of colorectal cancer risk factors in Hispanic populations, leading to improved screening and prevention strategies.
How similar studies have performed: While studies on familial colorectal cancer exist, this specific focus on the Hispanic population in Puerto Rico is novel and has not been extensively explored.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion criteria: * patients with colon polyps or colon cancer * patients will have a colonoscopy or colon surgery to treat a benign condition such as fissure, fistula, or hemorrhoids Exclusion criteria: Participation in this study is limited to persons 15 years or older with colon polyps or colon cancer and control subjects 21 years or older with no malignant conditions in the colon and / or rectum. Controls between the ages of 15 to 20 years will be not evaluated. The reason is colon cancer occurs in people under 21 years, except in special cases associated with certain genetic causes. People who cannot sign the consent may not participate in this study.
Where this trial is running
San Juan and 1 other locations
- Oncologic Hospital — San Juan, Puerto Rico (Recruiting)
- University of Puerto Rico Comprehensive Cancer Center — San Juan, Puerto Rico (Recruiting)
Study contacts
- Principal investigator: Marcia R. Cruz-Correa, MD, PhD — University of Puerto Rico
- Study coordinator: Marcia R. Cruz-Correa, MD, PhD
- Email: marcia.cruz1@upr.edu
- Phone: 787-772-8300
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.