Registry for essential low blood pressure and its related conditions
Essential Arterial Hypotension and Allostasis Registry
This study is trying to see how low blood pressure affects people of all ages and genders in Medellin, Colombia, and how it might be linked to other health issues like depression and fibromyalgia.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 5000 (estimated) |
| Sex | All |
| Sponsor | CES University Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Medellín, Antioquia) |
| Trial ID | NCT02018497 on ClinicalTrials.gov |
What this trial studies
This observational registry aims to explore the relationship between essential arterial hypotension and various comorbidities, such as depression and fibromyalgia, by assessing patients' blood pressure responses to daily life stressors. Patients of any age and gender visiting a cardiologist in Medellin, Colombia, will be recruited and classified based on their blood pressure and allostatic responses. The study will follow these patients over time to identify the development of diseases related to their blood pressure classification.
Who should consider this trial
Good fit: Ideal candidates include patients of any age and gender who experience essential arterial hypotension.
Not a fit: Patients with non-correctable secondary causes of blood pressure abnormalities or severe comorbid conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of essential low blood pressure and its associated conditions.
How similar studies have performed: While the approach of linking blood pressure disorders to allostatic responses is innovative, similar observational studies have shown promise in understanding comorbidities associated with blood pressure variations.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Any patient regardless of the age of gender Exclusion Criteria: * Any non-correctable secondary cause of increase or decrease in blood pressure * or a pathology that alters the prognosis before the entrance of the patient into this registry. * nephropathy prior to the admission, * familial dyslipidemia, * previous gastric bypass, * pre-existing heart failure, * chemotherapy-induced cardiotoxicity, * arrhythmogenic right ventricular dysplasia, * long QT syndrome, * hypertrophic cardiomyopathy * restrictive cardiomyopathy or sudden death syndromes other than coronary disease * Down syndrome, * having one single kidney before entering to this registry, * polycystic kidney, * disability to continue with the treatment * organ transplantation (other than cornea), * HIV positive, * homocystinuria, * myelomeningocele, * autoimmune diseases, * paraplegia, * chronic infections (TB), * myocarditis of any cause, * blood dyscrasia with coagulation disorders, * history of pulmonary embolism, * sustained or non-sustained ventricular tachycardia, * idiopathic tachycardia associated with syncope which is not cured by radiofrequency ablation, * pulmonary hypertension, * diabetes insipidus, * COPD, * Gitelman syndrome, * Cervical cancer associated with human Papillomavirus, * multiple sclerosis, * hemochromatosis, * not compact ventricle. It is important to emphasize that all of these patients, currently excluded from the registry, may be studied in the future, they keep on follow-up and taken 6 BP. Additionally it is planned to compare the evolution of patients with secondary causes of hypertension or hypotension with essential disorders
Where this trial is running
Medellín, Antioquia
- CES University — Medellín, Antioquia, Colombia (Recruiting)
Study contacts
- Principal investigator: Luis Eduardo Medina, MD. — Researcher
- Study coordinator: Luis Eduardo Medina, MD.
- Email: essentialhypotension@gmail.com
- Phone: (574)2323218
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.