Reducing iodinated contrast in hospital wastewater using a dedicated urine collection device after CT scans
Official title: GREENWATER 2.0: Cutting Edge Solution for Reducing Iodinated Contrast Agents Via Post-Administration Collection Device
Run by I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio · NCT07620093 · Data updated 2026-11-12
This study tests whether using a special urine collection device after contrast CT scans can help recover iodinated contrast and reduce wastewater in adult outpatients.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 416 (estimated) |
| Sponsor | I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio Academic / other |
| Locations | 1 site (Milan, MI) |
| Status | Recruiting |
| Started | March 10, 2026 |
| Main results expected | September 2026 |
| Study ends | December 2026 |
| Registry record updated | June 24, 2026 |
| Trial ID | NCT07620093 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adult patients (18+) scheduled for clinically indicated contrast-enhanced CT scans who can provide informed consent and are willing to wait ~60 minutes after contrast administration to use the urine collection device.
✕Probably not a fit
Patients who cannot use the urine collection device or who do not consent to post-contrast urine collection may not benefit from the approach.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
GREENWATER 2.0 is a single-center, prospective observational study in which adult outpatients undergoing clinically indicated contrast-enhanced CT scans use a dedicated urine collection device for about 60 minutes after injection. The study does not alter the imaging procedure, contrast agent, dose, or protocol; it only adds a post-scan urine collection step to measure how much contrast can be recovered and to assess patient acceptance. Primary questions focus on patient acceptance/compliance with post-contrast urine collection and the amount of iodinated contrast recovered from urine. Results will inform feasibility of integrating urine collection into radiology workflow to potentially reduce hospital wastewater contamination.
Why it matters
Potential benefit: If successful, this approach could enable recovery of iodinated contrast from urine and reduce environmental impact of hospital wastewater.
How similar studies have gone: The prior GREENWATER study indicated high patient willingness to participate in a post-contrast urine collection protocol, supporting feasibility but not proving environmental impact.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients aged 18 years or older. * Patients scheduled for a clinically indicated contrast-enhanced CT scan with iodinated contrast agent. * Patients able to provide written informed consent. * Patients willing to wait approximately 60 minutes after contrast injection before using the dedicated urine collection device. Exclusion Criteria: \- Patients unable to use the dedicated urine collection device for urine collection.
Where it's running
-
IRCCS Ospedale Galeazzi - Sant'Ambrogio
Milan, Mi, Italy Recruiting
Study contacts
- Study coordinator: Luca Maria Sconfienza, MD, PhD
- Email: io@lucasconfienza.it
- Phone: +390283502227
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.