Metabolomics and Transcriptomics of Gliomas

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study will analyze tumor samples to map the metabolites and transcripts that distinguish glioma subtypes. The goal is to identify clinically relevant molecular subgroups and to improve cellular and animal models used in drug development for these tumors. Participants will undergo standard care; only a small amount of resected tumor tissue will be used for advanced analyses. The study addresses both prognosis-driven subgrouping and model establishment to aid future therapies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Subjects who sign the informed consent form for study participation
* Males and females
* Age ≥ 18 years
* Patients with a radiological diagnosis of central nervous system enlargement on routine preoperative clinical imaging (MRI/PET) who will attend the OU outpatient clinics or the OGSA Emergency Department and are candidates for surgery
* Availability of medical history.

Exclusion Criteria:

* Age \< 18 years
* Subjects unable to understand and freely provide consent to the study
* Current pregnancy and/or breastfeeding (self-declaration).

Where it's running

• IRCCS Galeazzi-Sant'Ambrogio
  Milan, Lombardy, Italy Recruiting

Study contacts

• Study coordinator: Marco Rossi, MD
• Email: marco.rossi2@unimi.it
• Phone: +390283502228

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.