How to prevent post-surgery skin infections in bedridden patients
Official title: Evaluation of a Bundle of Actions to Prevent Skin Infections
Run by I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio · NCT07848269 · Data updated 2026-11-12
This study tests whether two cleaning methods for the skin of bedridden patients after major surgery can reduce skin bacteria more effectively than a standard sponge method.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 164 (estimated) |
| Sponsor | I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio Academic / other |
| Locations | 1 site (Milan) |
| Status | Recruiting |
| Started | September 20, 2026 |
| Main results expected | March 1, 2027 |
| Study ends | December 31, 2027 |
| Registry record updated | October 27, 2026 |
| Trial ID | NCT07848269 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults over 18 with ASA III status undergoing major elective surgery and requiring postoperative bed rest, able to consent.
✕Probably not a fit
Patients not experiencing reduced bacterial load or improved skin cleanliness with the tested methods may receive no benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The trial compares two cleaning approaches for the skin of bedridden patients after major elective surgery to see which method lowers bacterial load and maintains skin pH. Daily assessments over three days include measuring skin pH, performing culture tests, and timing the cleaning procedure. The study focuses on preventing post-surgical skin infections during the immediate postoperative period in ASA III patients. It uses a randomized-like comparison between swab-based cleaning and a sponge-based detersion method. Outcomes will help determine if one method offers better hygiene efficiency and infection prevention potential.
Why it matters
Potential benefit: If successful, patients may experience fewer skin infections and more efficient postoperative hygiene practices.
How similar studies have gone: Previous work has explored skin cleaning methods, with mixed results; this study adds direct comparison in a high-risk, bedridden postoperative population.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age over 18 - * Both sexes * ASA III with need of monitoring * Major surgery (Hip, Knee- Shoulder-first or revision) Exclusion Criteria: * Lack of consent * Poor cooperation * Post-operative delirium * Pregnant women
Where it's running
-
Istituto Clinico San Siro
Milan, Italy Recruiting
Study contacts
- Principal investigator: Giorgio Oriani — IRCCS OGSA - Site Istituto San Siro
- Study coordinator: Giorgio Oriani, Physician - Anesthetist
- Email: giorgio.oriani@grupposandonato.it
- Phone: +39335225452
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.