Clinical trial Recruiting at 1 site Interventional Ages 18 and up

How to prevent post-surgery skin infections in bedridden patients

Official title: Evaluation of a Bundle of Actions to Prevent Skin Infections

Run by I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio · NCT07848269 · Data updated 2026-11-12

This study tests whether two cleaning methods for the skin of bedridden patients after major surgery can reduce skin bacteria more effectively than a standard sponge method.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment164 (estimated)
SponsorI.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Academic / other
Locations1 site (Milan)
StatusRecruiting
StartedSeptember 20, 2026
Main results expectedMarch 1, 2027
Study endsDecember 31, 2027
Registry record updatedOctober 27, 2026
Trial IDNCT07848269 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults over 18 with ASA III status undergoing major elective surgery and requiring postoperative bed rest, able to consent.

Probably not a fit

Patients not experiencing reduced bacterial load or improved skin cleanliness with the tested methods may receive no benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial compares two cleaning approaches for the skin of bedridden patients after major elective surgery to see which method lowers bacterial load and maintains skin pH. Daily assessments over three days include measuring skin pH, performing culture tests, and timing the cleaning procedure. The study focuses on preventing post-surgical skin infections during the immediate postoperative period in ASA III patients. It uses a randomized-like comparison between swab-based cleaning and a sponge-based detersion method. Outcomes will help determine if one method offers better hygiene efficiency and infection prevention potential.

Why it matters

Potential benefit: If successful, patients may experience fewer skin infections and more efficient postoperative hygiene practices.

How similar studies have gone: Previous work has explored skin cleaning methods, with mixed results; this study adds direct comparison in a high-risk, bedridden postoperative population.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age over 18 -
* Both sexes
* ASA III with need of monitoring
* Major surgery (Hip, Knee- Shoulder-first or revision)

Exclusion Criteria:

* Lack of consent
* Poor cooperation
* Post-operative delirium
* Pregnant women

Where it's running

  • Istituto Clinico San Siro
    Milan, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.