Real-time engagement app to improve glycemic control in adolescents and young adults with type 2 diabetes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

REFLECT2D tests whether real-time, linked glucose and health-behavior data via a mobile app can improve glycemic control in adolescents and young adults with type 2 diabetes. After an education session and run-in, participants undergo a 90-day micro-randomized trial assigning them to a daily prompt focused on physical activity, a prompt focused on diet, or no prompt, followed by a 90-day observation period. Participants wear a continuous glucose monitor and a fitness tracker, use the app for 6 months, and provide occasional dietary logs and in-person visits with fasting blood draws. The study evaluates short- and longer-term changes in glycemic control and the persistence of these changes after prompts end.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* type 2 diabetes: negative diabetes autoantibodies, no suspicion for monogenic diabetes
* English-speaking (app in English)

Exclusion Criteria:

* Current pregnancy
* Hydroxyurea use (CGM sensor inaccuracies)
* Cognitive impairment or severe psychiatric condition that could interfere with participation in behavioral intervention for diabetes self-management
* Current or previously diagnosed eating disorder

Where it's running

• UPMC Children's Hospital of Pittsburgh
  Pittsburgh, Pennsylvania, United States Recruiting

Study contacts

• Principal investigator: Mary Ellen Vajravelu, MD — University of Pittsburgh
• Study coordinator: Mary Ellen Vajravelu, MD
• Email: vajravelume@upmc.edu
• Phone: 412-692-6533

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.