Quiet Knee Protocol after knee replacement

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective randomized trial compares the Quiet Knee Protocol to standard postoperative rehabilitation in adults undergoing unilateral primary total knee arthroplasty for osteoarthritis. Participants complete questionnaires and are followed for 12 months to assess pain control, range of motion, functional recovery, opioid use, and satisfaction. The study also looks at whether the protocol reduces the need for formal physical therapy and rates of manipulation under anesthesia. Primary care teams at Mayo Clinic and collaborators will supervise the two rehabilitation strategies and collect outcome data. The trial emphasizes adherence to assigned rehabilitation and excludes certain prior knee procedures and conditions that could affect mobility.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults (≥18 years) undergoing unilateral primary TKA for osteoarthritis
* Willingness to adhere to the assigned rehabilitation protocol
* Ability to provide informed consent

Exclusion Criteria:

* Revision TKA or bilateral procedures
* Preexisting neuromuscular disorders affecting mobility
* Prior knee surgery within 12 months
* No Joint Hardware
* Agree to avoid plane trips post-surgery for 2 weeks
* Patients with 100-degree flexion contracture
* Pregnant subjects

Where it's running

• Mayo Clinic
  Jacksonville, Florida, United States Recruiting
• Hospital for Special Surgery
  New York, New York, United States Not yet recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.