Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Immersive Virtual Reality and Exercise Programs for Multiple Sclerosis

Official title: Effects of a Physiotherapy Program With High-Intensity Exercise and Immersive Virtual Reality in Multiple Sclerosis: Randomized Controlled Trial

Run by University of Vigo · NCT07738120 · Data updated 2026-11-12

Aims to see if a VR-based exercise program helps adults with MS improve mobility and fitness.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment30 (estimated)
SponsorUniversity of Vigo
Academic / other
Locations1 site (Pontevedra)
StatusRecruiting
StartedOctober 6, 2025
Main results expectedJuly 31, 2026
Study endsAugust 7, 2026
Registry record updatedJuly 31, 2026
Trial IDNCT07738120 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults with confirmed MS, stable disease (no relapse in 6 weeks), able to perform moderate exercise, and engaged with a neurologist and patient association.

Probably not a fit

Patients with significant visual or vestibular impairment, recent changes in disease-modifying therapy, or other conditions hindering VR participation may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study explores a virtual reality–assisted exercise program combined with standard rehabilitation for adults with multiple sclerosis. Participants with stable MS and the ability to perform moderate exercise will engage in a VR-enhanced physical therapy regimen alongside routine rehabilitation. The trial will assess outcomes related to gait, balance, cardiorespiratory fitness, and quality of life. Eligibility requires confirmed MS, age 18 or older, no relapse in the last six weeks, and capacity to consent. The study is led by the University of Vigo with collaborating hospitals and patient associations in Galicia, Spain.

Why it matters

Potential benefit: If successful, participants may experience improved balance, walking ability, endurance, and daily functioning.

How similar studies have gone: Previous studies using VR in MS suggest potential improvements in motor function and engagement, though results vary by program design.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ≥18 years of age.
* Confirmed diagnosis of MS.
* Stable disease with no relapse in the previous 6 weeks.
* Patients who will be take follow up by a neurologist at the referral hospital and will be members of the patient association.
* Ability to perform moderate exercise.
* Capacity to provide informed consent.

Exclusion Criteria:

* Comorbidities that hinder the development of the VR program
* Visual or vestibular impairment that would contraindicate VR use.
* Recent changes in disease modifying therapy.

Where it's running

  • University of Vigo
    Pontevedra, Spain
    Recruiting

Study contacts

  • Principal investigator: Pablo Campo-Prieto, PhD — University of Vigo
  • Study coordinator: Pablo Campo-Prieto, PhD
  • Email: pcampo@uvigo.gal
  • Phone: 986801770

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.