Psychiatric Symptoms in Methamphetamine Psychosis With or Without Lifetime Cannabis Use

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective cohort follows adults with methamphetamine-induced psychotic disorder (MP) who are hospitalized in Elazığ, Turkey. Participants are split into those with lifetime cannabis use and those without, and weekly psychiatric assessments are collected over eight weeks. The study uses standardized scales to track symptom severity and related clinical features. It aims to identify factors that influence symptom progression and whether cannabis exposure alters outcomes in MP.

Why it matters

Who can join: the full rules

1. For Methamphetamine-Induced Psychotic Disorder plus Lifetime Cannabis Use (MP + LCU) Group:

   \*Inclusion Criteria:

   • Diagnosis of MP according to DSM-5-TR
   * Diagnosis of Cannabis Use Disorder according to DSM-5-TR
   * Medication-free for at least one month prior to admission
   * Age ≥ 18 years and \<65 years
   * Provided informed consent

   For Methamphetamine-Induced Psychotic Disorder plus Lifetime Cannabis Use (MP + LCU) Group:

   \*Exclusion Criteria:

   • Hypertension

   • Diabetes mellitus

   • Chronic kidney disease

   • Rheumatoid arthritis

   • Systemic lupus erythematosus

   • Cardiac illness
   * Severe neurological disorders
   * Immunological or systemic illness
   * Primary psychiatric disorders other than MP
   * Alcohol use disorder
2. For Methamphetamine-Induced Psychotic Disorder (MP without LCU) Group:

   \*Inclusion Criteria:

   • Diagnosis of MP according to DSM-5-TR

   • Medication-free for at least one month prior to admission

   • Age ≥ 18 years and \<65 years

   • Provided informed consent

   For Methamphetamine-Induced Psychotic Disorder (MP without LCU) Group:

   \*Exclusion Criteria:

   • Hypertension

   • Diabetes mellitus

   • Chronic kidney disease
   * Rheumatoid arthritis
   * Systemic lupus erythematosus
   * Cardiac illness
   * Severe neurological disorders
   * Immunological or systemic illness
   * Primary psychiatric disorders other than MP
   * Alcohol use disorder

Where it's running

• Elazığ Mental Health and Diseases Hospital
  Elâzığ, Elâzığ, Turkey (Türkiye) Recruiting
• Elazığ Mental Health and Diseases Hospital
  Elâzığ, Elâzığ, Turkey (Türkiye) Not yet recruiting

Study contacts

• Study coordinator: Mehmet Hamdi ÖRÜM, MD, Assoc. Prof., Psychiatrist
• Email: mhorum@hotmail.com
• Phone: +905382207558

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.