Clinical trial Recruiting at 2 sites Interventional Ages 18 and up

Promoting Palliative Care for Heart Failure Patients

Official title: Promoting Palliative Care for People With Heart Failure: The P3HF Pilot Study

Run by Yale University · NCT06933875 · Data updated 2026-11-12

This trial tests a clinical decision tool that helps clinicians refer hospitalized heart failure patients to palliative care sooner to see if it improves care alignment with patients' goals.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment2260 (estimated)
SponsorYale University
Academic / other
Locations2 sites (New Haven, Connecticut and 1 other locations)
StatusRecruiting
StartedJuly 2, 2026
Main results expectedOctober 30, 2027
Study endsOctober 30, 2027
Registry record updatedJuly 16, 2026
Trial IDNCT06933875 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Hospitals on the study teams: attending physicians, fellows, residents, advanced practice providers, Palliative Care team members, and related hospital staff involved in admission decisions; patients with acute heart failure meeting age, biomarker, and treatment criteria during hospitalization.

Probably not a fit

Patients whose care plans are not influenced by the tool or whose prognosis does not align with palliative care timing may not experience direct benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Healthcare providers at two Yale-affiliated hospitals will use a new clinical decision support tool integrated with a validated 1-year mortality risk model to prompt timely palliative care referrals for hospitalized heart failure patients. Eligible providers include attending physicians, trainees, nurse practitioners, physician assistants, and palliative care or quality/safety staff who have hospital privileges and are on admitting teams. Patients must be adults with heart failure, elevated NT-proBNP, and recent IV diuretic use during admission. The trial compares standard care to care augmented by the decision support tool, with post-trial surveys and interviews to assess feasibility and impact on care planning.

Why it matters

Potential benefit: If successful, the tool could increase timely palliative care referral and support goal-concordant treatment for heart failure patients.

How similar studies have gone: Prior use of prognostic CDS in this area has yielded mixed results, making this approach exploratory and potentially innovative for improving referrals.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Healthcare providers must meet the following criteria:

* Are an attending physician, fellow, or resident, advanced practice nurse, or physician associate
* Has ordering privileges
* Are members of one of the hospitals' admitting teams (e.g., hospitalist service, cardiology service)
* Anticipate employment at one of the two study sites for the 15-month trial period.

Or

* Palliative care team member
* Hospital administrator/quality and safety personnel

Patients of providers enrolled in the study must meet the following criteria for heart failure during hospitalization:

* Age 18 years of age or older
* N-terminal pro-B-type natriuretic peptide values of \>500 pg/ml
* Received intravenous diuretics within 24 hours of admission.

Exclusion Criteria:

* Pregnant at the time of admission.

Where it's running

  • Yale New Haven Hospital Saint Raphael
    New Haven, Connecticut, United States
    Recruiting
  • Yale New Haven Hospital York Street
    New Haven, Connecticut, United States
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.