Promoting Palliative Care for Heart Failure Patients
Official title: Promoting Palliative Care for People With Heart Failure: The P3HF Pilot Study
Run by Yale University · NCT06933875 · Data updated 2026-11-12
This trial tests a clinical decision tool that helps clinicians refer hospitalized heart failure patients to palliative care sooner to see if it improves care alignment with patients' goals.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 2260 (estimated) |
| Sponsor | Yale University Academic / other |
| Locations | 2 sites (New Haven, Connecticut and 1 other locations) |
| Status | Recruiting |
| Started | July 2, 2026 |
| Main results expected | October 30, 2027 |
| Study ends | October 30, 2027 |
| Registry record updated | July 16, 2026 |
| Trial ID | NCT06933875 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Hospitals on the study teams: attending physicians, fellows, residents, advanced practice providers, Palliative Care team members, and related hospital staff involved in admission decisions; patients with acute heart failure meeting age, biomarker, and treatment criteria during hospitalization.
✕Probably not a fit
Patients whose care plans are not influenced by the tool or whose prognosis does not align with palliative care timing may not experience direct benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Healthcare providers at two Yale-affiliated hospitals will use a new clinical decision support tool integrated with a validated 1-year mortality risk model to prompt timely palliative care referrals for hospitalized heart failure patients. Eligible providers include attending physicians, trainees, nurse practitioners, physician assistants, and palliative care or quality/safety staff who have hospital privileges and are on admitting teams. Patients must be adults with heart failure, elevated NT-proBNP, and recent IV diuretic use during admission. The trial compares standard care to care augmented by the decision support tool, with post-trial surveys and interviews to assess feasibility and impact on care planning.
Why it matters
Potential benefit: If successful, the tool could increase timely palliative care referral and support goal-concordant treatment for heart failure patients.
How similar studies have gone: Prior use of prognostic CDS in this area has yielded mixed results, making this approach exploratory and potentially innovative for improving referrals.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Healthcare providers must meet the following criteria: * Are an attending physician, fellow, or resident, advanced practice nurse, or physician associate * Has ordering privileges * Are members of one of the hospitals' admitting teams (e.g., hospitalist service, cardiology service) * Anticipate employment at one of the two study sites for the 15-month trial period. Or * Palliative care team member * Hospital administrator/quality and safety personnel Patients of providers enrolled in the study must meet the following criteria for heart failure during hospitalization: * Age 18 years of age or older * N-terminal pro-B-type natriuretic peptide values of \>500 pg/ml * Received intravenous diuretics within 24 hours of admission. Exclusion Criteria: * Pregnant at the time of admission.
Where it's running
-
Yale New Haven Hospital Saint Raphael
New Haven, Connecticut, United States Recruiting -
Yale New Haven Hospital York Street
New Haven, Connecticut, United States Recruiting
Study contacts
- Principal investigator: Shelli Feder, PhD — Yale University
- Study coordinator: Shelli Feder, PhD
- Email: shelli.feder@yale.edu
- Phone: 937-239-2801
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Using Apple Watch data to predict heart failure outcomes
This study is testing if data from Apple Watches can help predict heart failure problems and the chances of needing to go back to the hospital for patients with heart failure.
-
Comparing Aortix Device to Diuretics for Acute Heart Failure
This study is testing whether the Aortix device can help people with acute heart failure who aren't responding to diuretics feel better compared to standard treatment.
-
Myocardial Energetics Across Cardiovascular Disease Spectrum Using 31P-MRS
Researchers are testing whether phosphorus-31 magnetic resonance spectroscopy (31P-MRS) can map heart energy metabolism across healthy people and patients with various heart conditions.
-
Tailored digital support to cut sedentary time in long-term cardiac rehab
In adults in a long-term cardiac rehabilitation program, this study tests whether a personalized behavioural program with digital tools can reduce daily sitting time.
-
Prehospital end-of-life care: how professionals use a comfort care booklet in Strasbourg
This study tests how emergency crew members in Strasbourg use a comfort care booklet when caring for patients at end of life, and what they think about it.
-
NT-proBNP–guided heart failure screening for people 65+ in rural China
This study tests whether using NT-proBNP blood tests to guide heart failure screening in adults 65 and older in rural China can find unrecognized heart problems more effectively than symptom-based screening.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.