PRIORITY-CONNECT 2: virtual prehabilitation and recovery support for people having colorectal cancer surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

PRIORITY-CONNECT 2 is a pragmatic, randomised Type I hybrid effectiveness–implementation trial that compares an individualised, stepped multidisciplinary virtual (p)rehabilitation hub to usual care for patients undergoing elective colorectal cancer surgery. Around 564 participants will be randomised to the virtual hub or usual care, with a second randomisation assigning intervention participants to one of two hub sites. The virtual intervention delivers tailored input from physiotherapists, dietitians, psychologists, nurses, and social workers before and after surgery and can continue for up to 12 months depending on participant needs. The primary outcome is 30-day postoperative complications, with secondary outcomes including quality of life, days at home (DAH-30/90/365), quality of recovery, cost-effectiveness, and implementation metrics (RE-AIM).

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged ≥18 years undergoing elective major surgery for colon or rectal cancer with curative intent
* Consulting with a colorectal cancer surgeon at least 1 week prior to scheduled surgery

Exclusion Criteria:

* Patients undergoing Pelvic Exenteration (PE), Cytoreductive Surgery (CRS) with or without HIPEC, or concurrent surgery for metastatic disease
* Cognitive impairment such that they are unable to provide informed consent

Where it's running

• Coffs Harbour Health Campus
  Coffs Harbour, New South Wales, Australia Recruiting
• Chris O'Brien Lifehouse
  Sydney, New South Wales, Australia Recruiting
• Royal Prince Alfred Hospital
  Sydney, New South Wales, Australia Recruiting
• Royal Brisbane & Women's Hospital
  Brisbane, Queensland, Australia Recruiting
• Royal Adelaide Hospital
  Adelaide, South Australia, Australia Recruiting
• Modbury Hospital
  Adelaide, South Australia, Australia Recruiting

Study contacts

• Study coordinator: Daniel Steffens, PhD
• Email: Daniel.Steffens@health.nsw.gov.au
• Phone: +61 02 9515 3203

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.