Preventing ventilator dependence in children through early management techniques

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to develop a bundle treatment plan that includes early bedside rehabilitation, a nutrition program, and tracheotomy to prevent prolonged mechanical ventilation in children. By analyzing risk factors from previous studies, the researchers will implement these interventions at different time periods and compare outcomes with a control group. The goal is to reduce the incidence of ventilator dependence among stable children receiving mechanical ventilation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

（1）All stable children receiving mechanical ventilation

（1）Stable condition: respiratory rate does not exceed 20% of the basic respiratory rate, PEEP\< 8. 60%, VIS score\< 20, there is no hypotension (70mmHg+ age ×2, 70mmHg under one year old), no higher than the P95 of the same sex and age

Exclusion Criteria:

1. Status epilepticus
2. Active intracranial hemorrhage
3. Intracranial hypertension
4. Unstable fracture of the spine
5. Spinal cord injury
6. There are injuries that affect the implementation of rehabilitation
7. Acute surgery was performed on the same day.
8. Body temperature over 40℃
9. Brain function failure

Where it's running

• Children's hospital of Fudan University
  Shanghai, Shanghai Municipality, China Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Incremental Instrumental Dead Space vs Capping Trial Before Removing a Tracheostomy

  This study tests whether adding extra tubing to the ventilator circuit (without blocking the tube) helps decide when a patient is ready to breathe on their own after a tracheostomy better than the standard capping trial.

  Recruiting Pontificia Universidad Catolica de Chile · Santiago, Santiago Metropolitan · NCT07810166

• Powered lower-limb exoskeleton training for adults with prolonged mechanical ventilation

  We are testing whether using a powered leg exoskeleton during training can improve leg strength, breathing measures, and recovery time for people who have been on a ventilator for a long period.

  Recruiting Fu Jen Catholic University · New Taipei City · NCT07445035

• Bedside EIT-guided respiratory physiotherapy for adults on long-term ventilators

  This trial will test whether using bedside electrical impedance tomography to guide respiratory physiotherapy helps adults who have been on a ventilator for 21 days or more get more days off the ventilator within the first 28 days.

  Recruiting Capital Medical University · Beijing, Beijing Municipality · NCT07372794

• Low blood creatinine as a sign of longer ventilator use and a target for creatine supplements

  This project will test whether a low serum creatinine on admission predicts a longer need for mechanical ventilation and whether giving creatine supplements to post-ICU patients with low creatinine can shorten time on the ventilator.

  Recruiting at 2 sites University Hospital Ostrava · Brno and 1 other locations · NCT07177183

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.