Prevalence of cardiac amyloidosis in older patients with heart failure

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to determine the prevalence of cardiac amyloidosis in geriatric patients aged 80 years and older who have been hospitalized for heart failure with left ventricular hypertrophy. The study will recruit patients from 31 geriatric or cardiologic centers over a period of 24 months, with each participant being followed for 12 months. Data collected will include medical history, clinical data, frailty status, and results from bone scintigraphy to assess myocardial involvement. Follow-up will involve phone calls every three months to monitor hospitalizations and other health outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Aged ≥ 80 years
* Hospitalised for decompensation of heart failure in the last 12 months
* Subjects with hypertrophy of the septum or left ventricle at cardiac echography (defined as ≥ 12 mm)
* Subjects able to undergo a bone scintigraphy scan
* Subjects willing to participate

Exclusion Criteria:

* Subjects refusing to participate
* Subjects admitted to palliative care unit.
* Subjects under guardianship
* Subjects with a definite diagnosis of cardiac amyloidosis

Where it's running

• Geriatric Department, Broca Hospital
  Paris, IIe-de-France, France Recruiting
• CHU Nantes
  Nantes, Loire-Atlantique, France Recruiting
• CHU Poitiers
  Poitiers, New Aquitaine, France Recruiting
• CHU Rouen, Charles Nicole hospital
  Rouen, Normandy, France Recruiting
• CHU Montpellier
  Montpellier, Occitanie, France Recruiting
• CHU Toulouse
  Toulouse, Occitanie, France Recruiting

Study contacts

• Study coordinator: Isabelle Dufour
• Email: isabelle.dufour@gerondif.org
• Phone: +33 (0) 185781011

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Chest pain screening for hidden cardiac amyloidosis

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• Using advanced heart MRI to improve diagnosis and risk prediction for rare cardiomyopathies

  This project tests whether advanced cardiac MRI techniques can help diagnose and predict future risk for people with rare heart muscle diseases like Danon, Fabry, cardiac amyloidosis, Noonan syndrome, and cardiac sarcoidosis.

  Recruiting Chinese Academy of Medical Sciences, Fuwai Hospital · Beijing · NCT07336394

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.