Chest pain screening for hidden cardiac amyloidosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective observational study enrolling men older than 65 who present with chest pain but have no evidence of coronary artery disease on CT coronary angiography or Rb-PET. Participants will undergo blood and urine sampling, ECG, transthoracic echocardiography, and bone scintigraphy to look for signs of cardiac amyloid, with endomyocardial biopsy reserved for inconclusive cases. The primary aim is to determine the prevalence of cardiac amyloidosis in this defined chest-pain population. Data collected at Rigshospitalet will inform whether routine screening in similar patients is warranted.

Why it matters

Who can join: the full rules

Inclusion Criteria:

No signs of CAD through Rb-PET and/or CT coronary arteriogram

Exclusion Criteria:

Previous history of amyloidosis

Where it's running

• Rigshospitalet
  Copenhagen, Denmark Recruiting

Study contacts

• Study coordinator: Navid Noory, MD
• Email: navid.noory@regionh.dk
• Phone: 4535453108

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.